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Biomedical subjects

J K Lloyd

Publications and source records attributed to J K Lloyd.

At least 73 records · Page 4Linked to original sources
PubMed1974

The relative importance of the factors involved in the absorption of vitamin E in children.

The vitamin E status and ease of repletion in groups of children with coeliac disease, intestinal lymphangiectasia, and abetalipoproteinaemia was studied and compared with earlier studies in cystic fibrosis and obstructive jaundice. Each group represents an experimental model in which one of the transport steps involved in the absorption of vitamin E is defective or absent and thus the relative importance of these factors could be determined. Chylomicron formation and an adequate intraluminal concentration of bile salts were found to be the most important factors for the efficient absorption of the vitamin. The results in the five groups of patients have therapeutic implications if it is considered desirable to correct vitamin E deficiency states.

Abetalipoproteinemia↗
PubMed1973

Childhood obesity.

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Adipose Tissue↗
PubMed1972

Prospective study of serum cholesterol levels during first year of life.

A longitudinal prospective study of serum cholesterol concentrations during the first year of life has been carried out in 302 healthy babies. The results show that serum cholesterol estimations in cord blood cannot be used as a screening test for the diagnosis of familial hypercholesterolaemia. The only child subsequently found to have the condition had a cord serum cholesterol of 85 mg/100 ml compared with the mean value for the group of 78 mg/100 ml. The babies who had cord values greater than 100 mg/100 ml had values distributed throughout the normal range when re-examined at 1 year of age. Serum cholesterol concentrations during the early months of life were markedly influenced by the type of milk fed; it is suggested that investigations to establish the diagnosis of familial hypercholesterolaemia are deferred until the child is about 1 year old and feeding with cows' milk and mixed diet is established.Values obtained for serum cholesterol concentrations (mg/100 ml, mean +/- 1 S.D.) in healthy infants in this study were: at birth 78 +/- 23, at 1 week 155 +/- 31, at 6 weeks 155 +/- 31, at 4 months 184 +/- 36, at 8 months 195 +/- 37, and at 1 year 191 +/- 36.

Adolescent↗
PubMed1972

Relation between age of onset of obesity and size and number of adipose cells.

The size and number of adipose cells in obese children and adults were compared with control data. An increase in adipose cell size was found in all the obese subjects. The total number of adipose cells was increased in those children who had become obese already by the age of 1 year and in those adults who dated their obesity to childhood.

Adipose Tissue↗