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J K Porter

Publications and source records attributed to J K Porter.

40 records · Page 3Linked to original sources
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Determination of epimeric 1-(3-indolyl) propane -1,2,3-triol isolated from Balansia epichloe.

Investigations into diseases in cattle grazing on grass pastures infected with clavicipitaceous fungi have resulted in the isolation and characterization of erythro and threo 1-(3-indolyl) propane-1,2,3-triol from cultures of Balansia epichloë (Weese). Gas chromatography-mass spectroscopy analyses of synthetic and natural epimers as their trimethylsilyl derivatives is described. Toxicity studies with fertile chicken eggs demonstrated that the threo epimer was the more active compound. The ratio of erythro to threo was calculated at 3:2 in the natural isolate.

Animals↗
PubMedDate not supplied

[Ergot alkaloids and alkaloids from other endophytes, responsible for causing toxic syndrome in cattle after eating contaminated grass].

Different signs of ergotism in livestock associated with animals consuming feed grains and pasture grasses infected by Clavicipitaceae (e.g. Balansia spp. and Acremonium spp.) have been considered. Endophyte-infected tall fescue causes the damage to livestock, and its toxicity and ryegrass in livestock are associated with ergopeptide alkaloid ergovaline and indole-isoprenoid lolitrems produced by A. coenophialum and A. lolii. The role of another compound attendant to endophyte-infected fescue such as peramine and loline alkaloid is discussed. Concentration of alkaloids depends upon the season and the period of growing plant-host. The advantages and the problems of endophyte-grass mutualistic symbiosis in pasture conditions are considered. The perspective of genetic manipulation of grass and fungus to produce endophyte-infected grasses with stress and insect deterences without affecting ruminant health.

Alkaloids↗