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J K Pye

Publications and source records attributed to J K Pye.

21 records · Page 2Linked to original sources

A case of Masson's vegetant, intravascular haemangioendothelioma presenting in a large neck vein.

Masson's vegetant intravascular haemangioendothelioma is a rare, benign, intravascular tumour. It is often associated with a pre-existing vascular process such as a pyogenic granuloma or a haemangioma. The clinical diagnosis is usually that of a vascular lesion or of a cyst. This is the first report of such a lesion presenting in a large neck vein. It is important to recognize the existence of this tumour as it is invariably benign, and local excision is curative.

Female↗

Automated oesophageal reflux sampler--a new device used to monitor bile acid reflux in patients with gastro-oesophageal reflux disease.

A new automated suction device has been developed to aspirate the contents of the distal oesophagus to monitor the constituents of the refluxate in patients with gastro-oesophageal reflux disease. Using antimony and glass electrodes with solid-state pH recorders it has been conclusively shown that gastric acid is responsible for the mucosal damage seen in reflux oesophagitis but new evidence is emerging that other constituents of the gastroduodenal juice, in particular bile acids, are also damaging to the oesophageal mucosa. The main difficulty lies in that there is no reliable method of monitoring this component of the refluxate except by direct aspiration of the contents for assay. This new technique of oesophageal sampling utilizing a software-controlled suction process with simultaneous pH recording has helped to identify patients at risk of refluxing potentially harmful substances and is a valuable addition to the armamentarium of investigative procedures for patients with gastro-oesophageal reflux disease.

Bile Reflux↗