PubMed HealthSearch

Biomedical subjects

J K Torng

Publications and source records attributed to J K Torng.

At least 19 recordsLinked to original sources

The contralateral variation of peak systolic velocity in common carotid arteries.

In order to evaluate the contralateral variation of the peak systolic velocity (Vmax) in common carotid arteries (CCAs), 9 clinically healthy persons (Group A), 11 patients with simple goiter (Group B) and 16 patients with diffuse toxic goiter (Graves' disease, Group C) were referred for radionuclide scanning, duplex Doppler ultrasonography (duplex US) and determination of serum level of the thyroid hormones (T3, T4, T3U) by radioimmunoassay. In Group A, Vmax of right CCA was 98.8 +/- 34.5 cm/sec and that of left CCA was 113.4 +/- 28.9 cm/sec; the left CCA had a higher blood flow velocity than the right one in normal subjects (p less than 0.01). However, the left and right CCA Vmaxes did not significantly differ to each other in Group B (93.5 +/- 21.4 cm/sec vs 98.6 +/- 21.4 cm/sec, p greater than 0.05) and Group C (146.9 +/- 29.3 cm/sec vs 149.9 +/- 28.9 cm/sec, p greater than 0.05). We conclude that there is a contralateral difference of blood flow velocity of common carotid arteries with the left value higher than the right one in healthy persons and this should be kept in mind in evaluation of thyroid functional and carotid arterial diseases.

Adult

The peak systolic velocity of the common carotid artery and superior thyroid artery as an indicator of thyroid function.

We investigated the efficacy of color duplex ultrasound in the detection of the thyroid's functional state on 132 consecutive patients referred for morphological examination of the thyroid gland. The patients were classified into 3 groups: Group A (euthyroid, n = 108), Group B (diffuse toxic goiter, n = 16) and Group C (hyperthyroidism on medical treatment for 1 to 4 months, n = 8), according to the serum thyroid hormones' determination and the patient's clinical history. The peak systolic velocity (Vmax) of the bilateral common carotid arteries (CCAs) and superior thyroid arteries (STAs) were measured. The Vmax of CCAs was 90.33 +/- 23.13 cm/sec (mean +/- standard deviation), 148.44 +/- 28.97 cm/sec and 84.75 +/- 13.58 cm/sec in Groups A, B and C. The hyperthyroid patients had a significantly higher Vmax of CCAs than the euthyroid subjects (p less than 0.001) and those hyperthyroid patients receiving medical treatment (p less than 0.001). The Vmax of STAs was 32.4 +/- 13.49 cm/sec for the non-nodular lobes and 38.78 +/- 13.76 cm/sec for the nodular lobes in the euthyroid subjects. There was no difference between the non-nodular and nodular lobes. The Vmax of STAs was 91.69 +/- 32.02 cm/sec and 62.75 +/- 18.19 cm/sec for Groups B and C; both were higher than the euthyroid (p less than 0.001 and p less than 0.05 respectively). Patients with hyperthyroidism had a lower Vmax of STAs after medical treatment (Group B vs Group C, p less than 0.01). It is our conclusion that cases of hyperthyroidism have a higher volume of blood flow of both the common carotid arteries and thyroid arteries than the euthyroid cases.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult

The changes of serum titers of thyroid antibodies in patients of Graves' disease with hyperthyroidism after treatments with antithyroid drugs.

In order to investigate the effect of antithyroid drugs on serum titers of antithyroglobulin and anti-thyroid microsomal antibody, these two antibody levels were studied in 38 patients of Graves' disease with hyperthyroidism before and after treatments with carbimazole or methimazole. The results showed no consistent changes in their titers. To explain the inconsistent findings as compared with other authors' studies, lower doses of antithyroid drugs were postulated as one of the causes.

Adolescent