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Biomedical subjects

J Kansy

Publications and source records attributed to J Kansy.

At least 19 recordsLinked to original sources
PubMed1989

Allogeneic bone marrow transplantation from HLA-identical siblings following conditioning with busulfan and cyclophosphamide. First results.

In the time period from November 1984 to January 1987 eight allogeneic bone marrow transplantation were performed from HLA-identical siblings. The theoretical chance of success in this group was between 21 and 50%, according to the recent data of the International Bone Marrow Transplant Registry, depending on the diagnosis and clinical condition. The average chance was 37.5%. Haemopoietic reconstitution was achieved in 6 recipients, while 2 died of early complications (cytostatic induced hepatocellular damage and fungal sepsis). Another 3 patients died of complications of the intermediate period (pulmonary bleeding, virus hepatitis, graft rejection). The remaining 3 recipients are alive, in excellent clinical condition, including one girl surviving more than 2 years after the transplantation.

Adolescent↗
PubMed1987

Success of bone marrow transplantation in congenital Diamond-Blackfan anaemia: a case report.

A 6-yr-old girl with congenital corticosteroid-resistant pure red cell aplasia was treated with bone marrow transplant from her HLA-identical, MLC-unreactive sister in November 1984 following conditioning with busulfan and cyclophosphamide. Full engraftment was obtained and the patient at 21 months post-transplant is in excellent clinical condition maintaining normal red cell counts. We conclude that BMT should be considered as a therapy for at least the most severe cases of Diamond-Blackfan anaemia resistant to corticosteroids. Successful outcome of this therapy provides an argument for the stem cell origin of this disorder.

Bone Marrow Transplantation↗
PubMed1981

Follow-up studies on surgical treatment of vesicoureteric reflux in 141 children.

The results of reimplantation of ureters in 141 children by a modified Politano-Leadbetter procedure are presented. 86 children were examined 3 to 13 years after operation. Cessation of signs of infection, reflux and ureteric obstruction was noted. The most common illnesses and congenital disorders of the urinary tract which accompany vesicoureteral reflux are discussed. Postoperative complications are also described.

Child↗