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Biomedical subjects

J Karnetová

Publications and source records attributed to J Karnetová.

5 recordsLinked to original sources
PubMed1988

Propionate and the production of monensins in Streptomyces cinnamonensis.

Variants resistant to propionate were prepared from a mutant strain of Streptomyces cinnamonensis producing predominantly monensin A. Using selected resistants the production of monensins (in media with higher concentrations of propionate) was examined. Stimulation of monensin synthesis by propionate was observed with 70% of the resistants studied. Propionate did not influence the ratio between monensin A and B production.

Drug Resistance, Microbial↗
PubMed1976

Microbial transformation of daunomycinone by Streptomyces aureofaciens B-96.

Daunomycinone, aglycone of the anthracycline antibiotic daunomycin, was transformed by a washed mycelia of Streptomyces aureofaciens B-96 in a buffer solution containing sucrose; the obtained product, dihydrodaunomycinone (9-(1-hydroxyethyl)-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-4-methoxy-5,12-naphthacenequinone), was identified by measuring basic physicochemical characteristics (IR, UV and visible spectra, mass spectra and NMR, optical rotation and m.p.).

Biotransformation↗