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Biomedical subjects

J Kepes

Publications and source records attributed to J Kepes.

8 recordsLinked to original sources

Hemiballism and tremor due to ependymal cyst.

A 21-year-old woman was admitted with right hemiballism and tremor. She had tremor since the age of 6 years. At age 12, an intracerebral, left paraventricular space-occupying lesion was found and treated with 4,500 rads. Increasing tremor was associated with mass enlargement. By age 20, there was insidious presentation of right hemiballism. At age 21, she had craniotomy and a large septate cyst was opened and drained. Biopsy of the cyst wall revealed that it was consistent with ependymal cyst. Postoperatively the hemiballism resolved and the tremor improved. This case is unusual due to the presentation of hemiballism caused by ependymal cyst.

Adult

Lyme neuroborreliosis manifesting as an intracranial mass lesion.

Lyme neuroborreliosis is one of the chronic manifestations of Lyme disease and is caused by the neurotropic spirochete, Borrelia burgdorferi. Two of the three stages of Lyme disease potentially involve the central nervous system: a second stage that may manifest as meningitis, cranial neuritis, or radiculoneuritis; and a third stage, or chronic neuroborreliosis, with parenchymal involvement. The tertiary stage may mimic many conditions, including multiple sclerosis, polyneuropathy, viral encephalitis, brain tumor, vasculitis, encephalopathy, psychiatric illness, and myelopathy. We report a 10-year-old child with signs, symptoms, and radiological manifestations of intracranial mass lesions, without previously recognized manifestations of Lyme disease. This proved to be Lyme neuroborreliosis, documented by histological and serological examination, which responded well to antibiotic therapy. The need to establish a tissue diagnosis of intracranial mass lesions is emphasized, and the utility of a computed tomographic-guided stereotactic system for this purpose is discussed.

Biopsy

[The differentiation of parts of paprika fruit by analysis of their mineral constituents].

In order to determine the trace metals and minor elements in the different parts of the paprika fruit (red pepper) samples were ashed and analysed by an emission spectrographic method. Analysis lines of 9 elements (B, P, Fe, Mg, Si, Mn, Al, Ca, Cu) were measured in the arc spectra of the samples, and the logarithmic intensity data processed by pattern recognition methods. From the data obtained the three components of the plant ("exocarp", "seed", and "stem") could be correctly classified. Mixtures of components were prepared at varying ratios and could be differentiated from the pure components with great reliability.

Condiments

Ganglia of the nerve. Presentation of two unusual cases, a review of the literature, and a discussion of pathogenesis.

Two cases of intraneural ganglia are reported: the first reported involvement of the sciatic nerve and the first reported involvement of the tibial nerve in the tarsal tunnel. Both were successfully treated by excision with sparing the neural elements leading to neurological recovery. A review of the literature fails to reveal any consensus that lesions arise from normal synovial cavities. Incision, evacuation, and complete excision under magnification sparing neural elements gives satisfactory results. Excision of the nerve is not indicated. Pathologic examination suggests that the lesion arises by multicentric metaplasia of connective tissue elements of the nerve rather than by invasion.

Adult