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Biomedical subjects

J Kingman

Publications and source records attributed to J Kingman.

9 recordsLinked to original sources
PubMed1984

Keratoacanthoma. A clinical study.

Keratoacanthoma (KA) is a relatively common tumor believed to be a benign epidermal neoplasm. Ninety patients with one or more KAs were observed in regard to clinical, therapeutic, and prognostic implications. In particular, we were able to analyze the relationship of KA to internal malignant neoplasms in 78 patients. Keratoacanthoma is a disease of the elderly (mean patient age, 64.1 years). It is associated with other nonmelanoma cutaneous neoplasias in 21% of cases, a figure lower than that seen with squamous cell carcinomas. When solitary, KA is not associated with concurrent or subsequent internal malignant neoplasms more often than would be predicted by population statistics. Therapy is generally curative, but about 8% of the patients had recurrences. These patients may be successfully treated with several existing modalities.

Adult↗
PubMed1984

Disseminated cutaneous Nocardia brasiliensis infection.

Nocardia brasiliensis is an uncommon pathogen in the United States despite its presence in soil samples. It is most frequently seen in patients who are immunosuppressed, but can occur in the immunocompetent host also. Usually in a healthy host the infection is localized to one area of the body. Disseminated infection was diagnosed in a healthy child who recovered fully after initiation of oral sulfonamide therapy. We suspect that the source was soil to which the patient was exposed during a family camping trip. Nocardia asteroides is the most frequent cause of nocardial infections in North America. These infections are unusual in healthy individuals, occurring more often in immunologically compromised hosts. They are usually acquired by a pulmonary route and may disseminate widely, most commonly to the central nervous system and skin. Nocardia brasiliensis, when it does occur in the United States, usually causes a chronic cutaneous and subcutaneous infection manifesting itself as mycetoma, abscess, or ulcer. We saw acute suppurative lymphocutaneous Nocardia brasiliensis infection in an otherwise healthy 2-year-old boy.

Child, Preschool↗
PubMed1983

Cutaneous vasculitis in systemic lupus erythematosus. A poor prognostic indicator.

The type of cutaneous lesion found in the patient with systemic lupus erythematosus is often predictive of the activity and course of the systemic disease. Vasculitis often correlates with active systemic lupus erythematosus, and portends a poor prognosis. A patient with several vasculitic changes on the fingers who died of progressive renal and central nervous system deterioration is presented.

Antibodies, Antinuclear↗