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Biomedical subjects

J Kirkpatrick

Publications and source records attributed to J Kirkpatrick.

25 records · Page 2Linked to original sources
PubMed1976

Periostitis and pseudoperiostitis.

Increased metabolic activity with the periosteum is demonstrated radiographically by the presence of a linear shadow of bone paralleling the cortex, most commonly reflecting increased osteoblastic activity and thus representing periosteal new bone. This is frequently seen in psoriatic arthritis and Reiter's syndrome. A similar picture occurs with increased osteoclastic activity and reflects rapid demineralization, simulating periostitis. This change must be recognized as a reflection of osteoporosis, lest the condition be misdiagnosed as inflammatory disease.

Arthritis↗
PubMed1976

alpha-L-iduronidase deficiency and possible Hurler-Scheie genetic compound. Clinical, pathologic, and biochemical findings.

The enzymatic delineation of the mucopolysaccharidoses has revealed that certain syndromes, although phenotypically distinct, share the same enzymatic defect. Patients with the classic Hurler and Scheie syndromes or other phenotypic variations of these two disorders have a deficiency of alpha-L-iduronidase. We are reporting a patient with alpha-L-iduronidase deficiency whose phenotypic abnormalities did not resemble either the Hurler or Scheie syndrome and who may have had either the Hurler-Scheie genetic compound described by McKusick or an allelic disorder. Our patient was a 25-year-old woman whose initial presentation was due to acute paranoia and who was subsequently found to have many morphologic, neurologic, radiographic, and neuropathologic findings consistent with a mucopolysaccharide disorder. To our knowledge, complete neuropathologic findings have not been previously described in this hybrid group of patients. A distinctive feature of this patient's illness is that the underlying disorder was not clinically apparent until adulthood, but presented with sever bony abnormalities of the skull and deposition of mucopolysaccharides in the meninges.

Adult↗
PubMed1974

Manifestations of the battered-child syndrome.

Between 1965 and 1972, 231 patients were admitted to St. Christopher's Hospital for Children in Philadelphia with the battered-child syndrome. The case records and reontgenograms of 217 patients were reviewed. About one-third of the patients repuired orthopaedic treatment. The purpose of this paper is to alert the orthopaedist to the existence and prevalence of the battered-child syndrome, to describe both the non-orthopaedic and the orthopaedic manifestations of this problem, and to delineate the orthopaedist's responsibility to the battered child and the child's family.

Battered Child Syndrome↗