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Biomedical subjects

J Kiszel

Publications and source records attributed to J Kiszel.

At least 37 records · Page 2Linked to original sources
PubMed1983

Effects of dopamine on renal functions in premature neonates with respiratory distress syndrome.

The renal effects of dopamine have been studied in preterm infants with RDS. Dopamine has been given in doses of 0.5-2.0 microgram/kg/min as a continuous intravenous infusion in cases of peripheral circulatory disturbances. As a result, the circulation became stable and some renal parameters improved. There was a + 106% increase of urine output as well as a + 73%, + 140%, + 21% increase in Na-excretion, FeNa, creatinine clearance respectively. In accordance with the marked increase in phosphorus excretion the titratable acidity was also increased. There was a significant decrease in the renal urea excretion and free water clearance. These alterations were probably caused by an intrarenal hemodynamic redistribution. The possible mechanism of the renal changes are also discussed. The observations demonstrate the functional maturity of renal dopaminergic receptors in the preterm infants.

Dopamine↗
PubMed1982

[Effects of furosemide on renal functions in prematures (author's transl)].

Renal effects of Furosemide were examined during the first 2-4 days of life in preterm infants suffering from respiratory distress syndrome. Administration of the drug was followed by a sevenfold increase of diuresis. This latter was a result of both a rise in sodium excretion and glomerular filtration. The possible mechanism of Furosemide induced alteration in the glomerular filtration is discussed. Furosemide also altered the hydrogen-ion excretion: both the urinary bicarbonate, the titratable acidity and the ammonium excretion increased. There was a significant rise in the net acid excretion and hydrogen clearance too. It has been found that besides its diuretic effect Furosemide might play a role in the renal hydrogen elimination.

Acid-Base Equilibrium↗
PubMed1981

[Tolazoline-HCl in cardio-respiratory adaptation of newborns with respiratory distress syndrome (author's transl)].

The pharmacological effects of Tolazoline were studied in newborns with different types of pulmonary diseases. The drug was given when the arterial pO2 remained below 6,65 kP in spite of PEEP, and when the right-to-left shunt was greater than 60%. Continuous monitoring of arterial blood pressure and pO2 were of particular importance. Permanent improvement was found in 50%. Transitional improvement in 30% of the cases and in the remaining 20% the drug had no observable effect.

Blood Circulation↗
PubMed1977

[Comparative studies of placentar diffusion of propanidid (Sombrevin) and barbiturate in premature pregnancies and cesarean sections].

The placental diffusion and fetal elimination of propanidid (Sombrevin) and hexobarbituralnatrium adhibited for the introduction of narcosis in cases of prematures requiring caesarean section is studied by virtue of maternal, umbilical cord, and new-born blood samples. On the basis of the results we come to the conclusion that for the introduction of narcosis in prematures requiring caesarean section, Sombrevin seems to be more suitable than hexobarbituralnatrium, owing to the quicker propanidid elimination.

Cesarean Section↗
PubMed1977

[Barbiturate determination in maternal as well as fetal serum during anesthesia of diabetic and non-diabetic pregnancies].

The rapid decrease of the hexobarbituralnatrium level is observed in the course of narcosis carried out on occasions of Caesarean section, when examining the development of the barbiturate blood level in the maternal, and umbilical blood taken at delivery, whilst in diabetic patients a delay and dragging tendency is observed in the decomposition rate of the hexobarbituralnatrium. The difference manifesting itself in the barbiturate elimination among diabetic and non-diabetic pregnancies, draws attention to the conscientious selection of drugs and doses employed in the course of narcosis during Caesarean section.

Anesthesia, Obstetrical↗