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Biomedical subjects

J Kjaer

Publications and source records attributed to J Kjaer.

9 recordsLinked to original sources

Comparative genetic resistance to Ascaridia galli infections of 4 different commercial layer-lines.

1. The objective of the study was to compare the establishment and effect of Asaridia galli infections in 4 different layer-lines. 2. A total of 160 birds comprising 4 different commercial layer-lines, ISA Brown, New Hampshire, Skalborg and a cross of New Hampshire(NH) and Skalborg (Sk), were infected with A. galli eggs. The birds were examined for the presence of parasite eggs and parasites at weeks 3, 6 and 9 post infection (pi). 3. At week 6 pi the chickens of the NH line harboured more larvae compared with the three otherlines. The Sk line chickens excreted more A. galli eggs throughout the study compared with the other lines. Female worms in the Sk line were more fecund than the worms in the other lines. Male and female worms recovered from the Sk line at week 9 pi were longer. Male worms recovered from the NH line 6 weeks pi were shorter than male worms from the other lines. Female worms recovered from the NH line were shorter than the female worms from the ISA line and the Sk line. No differences were seen in weight gain among the 4 lines. 4. The results suggest that genetic factors are involved in the establishment and survival of A. galli in the intestine of layers. Further studies are needed to elucidate the genetic mechanisms behind the observed parasitological findings.

Animals↗

Mechanical loosening after hip replacement. Incidence after 10 years in 125 patients.

From our first 186 Charnley hip replacements 125, retained for more than 10 years, were examined clinically and radiographically. There were radiographic signs of definite or probable loosening of one or both prosthetic components in 29 per cent of the hips. However, there was a poor correlation between the clinical and the radiographic results, as 86 per cent of the hips were free from significant pain. The loosening rate for males under 60 years of age at the time of the operation was four times higher than for females in the same age group. We suggest that this high-risk group should be followed radiographically, so that a revision, if necessary, can be considered while the bone stock is still sufficient.

Aged↗

The subchondral bone of the proximal tibial epiphysis in osteoarthritis of the knee.

The trabecular bone of the proximal end of the tibia was assessed as an endoprosthesis-bearing structure. The mass and mineral content as well as the activity of subchondral trabecular bone were determined in osteoarthritis knees with varus or valgus deformity. Bone specimens were taken from the lateral condyle, the medial condyle, and centrally from the intercondylar area of seven varus and four valgus knees. The percentage volume of trabecular bone was determined by histomorphometry. On an additional nine knees, five with varus and four with valgus deformity, as well as ten knees from a normal autopsy material, photon absorptiometric determination of the mineral content of the same areas was performed. On average, the loaded condyle had twice the percentage volume of trabecular bone, and accordingly twice the mineral content, of the unloaded condyle. It was remarkable that the mineral content of the latter was of the same order as the condyles of the normal material.

Aged↗