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Biomedical subjects

J Knof

Publications and source records attributed to J Knof.

6 recordsLinked to original sources
PubMed1978

Temperature distribution in tissue during laser irradiation.

During irradiation with an Ar+-and Kr+-laser the temperature rise in living and dead tissue was measured in various depths. The contribution of the blood flow to the heat transport during irradiation was found to be small. The influence of the different depths of penetration and backscattering at the blue-green Ar+-and the red Kr+-radiation was investigated. The measurements compared with theory show reasonable agreement for an one-dimensional model below 100 degrees C. The results are discussed with respect to laser application in medicine.

Animals↗
PubMed1978

A laser-endoscope with direct beam coupling.

An optical element for direct laser-beam coupling into the observation optic of a rigid endoscope was developed. Using this coupling element every suitable endoscope can be modified into a laser endoscope which can be used for laser surgery e.g. in ENT and urology. The requirements for the endoscope and the optical coupling element are discussed.

Endoscopes↗
PubMed1977

[Endonasal Ar+-laser beam guide system and first clinical application in vasomotor rhinitis (author's transl)].

First clinical experiences in the treatment of vasomotr rhinitis of 3 patients using an Ar+-laser are discussed. Punctiform and stripe laser lesions were produced on the lower human turbinates. Macroscopically the typical laser lesion consists of a central area of carbonisation surrounded by a sharply bordered zone of coagulation. Later a hyperemic margin arises. Some days after laser application an ulcus developes which is cleaned after some days. 20 days after laser application the wound is healed completely. The advantage of laser surgery is the absent of blood and pain if premedication and surface anesthesia are used. Laser surgery is compared with present-day surgical techniques for treatment of vasomotor rhinitis. Within the present time of observation of 6 months the patients are free of symptoms, if a sufficient laser surgical treatment took place. The laser surgical technique and the contruction of the laser beam guide system is described. At a laser power of 1.5-2 W and a beam diameter of 0.7 mm on the tissue the time of irradiation was several seconds on each lesion. The disadvantages of the laser technique are the high costs for the laser instrument and some technical problems with the nasal end tube.

Evaluation Studies as Topic↗