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Biomedical subjects

J Kolín

Publications and source records attributed to J Kolín.

15 recordsLinked to original sources

[Decentration of posterior chamber intraocular lenses].

In a group of 300 patients with a posterior chamber lens in 19% its decentration was found, in 2.3% the iris capture syndrome. The author discusses possible causes of decentration of the implanted lens, possibilities of its therapy.

Anterior Chamber

[Inflammatory intraocular complications after placement of retropupillary lenses].

In 194 patients aged 32-81 years 200 retropupillary lenses were administered. 129 lenses were implanted into the sulcus ciliaris, 71 lenses into the lenticular capsule. The surgical technique was the same in both groups. The authors divide inflammatory postoperative complications they encountered into two major groups: cellular reactions on the anterior surface of the lens and fibrinoid reactions with the formation of membranes or synechiae. The authors discuss possible reasons for the development of these complications and possibilities of therapy.

Adult

Periosteal Ewing's sarcoma.

Periosteal Ewing's sarcoma is an uncommon, but well documented origin of this malignant condition with radiographic signs, different from intramedullary growing tumours. Imaging modalities like CT or MRI supply proof of macroscopically intact endosteal cortical surface and free medullary cavity in long bones affected by this periosteal type of malignancy. Definite confirmation is valid after a careful microscopic investigation of the resected specimen. The prognosis of this type of Ewing's sarcoma may be more favourable than that of the central type. Early diagnosis and therapy are thus essential. A clinical survey of six observations is given.

Bone Neoplasms

[Extramedullary Ewing's sarcoma].

The authors refer to six observations of periostal Ewing's sarcoma and describe its X-ray symptomatology. It differs considerably from the commonly known picture of centrally, intramedullar-originated Ewing sarcomas and tumours, diagnosed at considerable advanced stage. The possibility of periosteal origin of Ewing's sarcoma must be considered in differential diagnosis of periostoses and the patients must be examined in a complex way, particularly by computer tomography (and in the future also by MR tomography) in order to demonstrate that the medullar space of the bone is not affected by the tumour. This enables a more considerate resection during the operation. Histological verification of the nature of the tumour and excluding presence of the tumour cells in bone marrow dissection material is necessary. It may be expected that prognosis of this form of Ewing's sarcoma while treated in a modern combined way is more favourable than in the central forms.

Adolescent

[Spinal stenosis].

Space conditions in the spine canal play the decisive role in the origin of neurological difficulties connected with pressure on the spinal cord and its radices. For the diagnosis of spinal stenosis the dimensions of the spine canal are of importance: sagital, interpedicular, interarticular and the width of lateral recessus of the spine canal. The diagnostics of spinal stenosis is based on the anterior-posterior and lateral picture of the spine, CT examination and contrast examination of the spine canal--myeloradiculography. CT is included in the diagnostic algorhythm on the 2nd place after picture of the spine in classical projections. The anvantage of CT in its non-invasiveness, illustration without projection distortion and high sensitivity and specificity of the examination. Myeloradiculography is indicated for cases of uncertain findings with CT or discrepancy of the CT picture and clinical condition. It may be presumed that in the near future the CT examination will be required in the diagnosis of spine stenosis more frequently by the physicians.

Humans

"Slimy eyes phenomenon" in mice intraperitoneally injected with Pseudomonas aeruginosa cells or cell products.

Mice intraperitoneally treated with various Pseudomonas aeruginosa products or lipopolysaccharides of some selected Enterobacteriaceae representatives were found also to react by an increased slime secretion of the eye conjunctivae. The condition, tentatively designated as "Slimy Eyes Phenomenon", started to develop shortly post-treatment, culminated within 24-48 h when the eyes became fully glued up with slime, and receded 48-72 h later, leaving no sequelae for the eye or the general condition of the animal. No such phenomenon has to date been observed in other laboratory animal species.

Animals