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Biomedical subjects

J Kondrová

Publications and source records attributed to J Kondrová.

11 recordsLinked to original sources
PubMed2000

[The retinal nerve fiber layer in glaucoma. II. The status of the nerve fiber layer and development of changes in the visual field. Prospective study].

PURPOSE: To determine whether retinal nerve fiber layer (RNFL) photographs can predict future glaucoma visual field damage. METHODS: In a prospective study 158 red free photographs of the RNFL were made from November 1994 to June 1995. 28 eyes of 19 patients with ocular hypertension (repeated intraocular pressure over 21 mmHg and normal visual fields--Peristat 433 Rodenstock--at first examination) could be re-examined for an average time of 42.3 (SD 4.5) months. RESULTS: Only in one eye with normal RNFL at the first examination typical glaucoma visual field defects appeared (6%), but in 6 of 12 eyes (50%) with photographically demonstrable RNFL defects. The difference was statistically significant. CONCLUSION: There is only a minor probability, that visual field defects would appear during 3-5 years in eyes with normal RNFL photographs (6%), but about 50% of eyes with originally found RNFL defects.

Adult↗
PubMed1998

[Changes in psychovisual function after central serous chorioretinopathy].

Psychovisual examination methods detect macular changes better and more subtly then hitherto commonly used examination methods, in particular in dynamic investigations. The authors used this method in a series of investigations of diabetes, glaucoma and haemodialysis. The group is formed by 19 eyes of 16 patients with a first attack of central serous chorioretinopathy. Two thirds of the patients were treated by conservative methods, one third by photocoagulation with an argon laser. The observation period was 3 months to 13 years, the mean being 3.5 years. The control group was formed by a group of healthy subjects of corresponding age. The authors proved a statistically significant (5%) reduction of the contrast sensitivity at medium spatial frequencies (6 and 12 c/dg) in patients with one or several attacks of CSCHR. Statistically significant deterioration of colour discrimination (5%) was proved in patients with one attack of CSCHR in 20% of the patients. In patients with two or more attacks of the disease the authors recorded a statistically significant deterioration of colour discrimination (1%) in 44% of the patients. They did not reveal, using psychovisual examination methods, statistically significant differences between groups of patients treated conservatively or by laser. In all cases of impaired colour discrimination a disorder in the blue-yellow region was involved, i.e. in the region of retinal receptors.

Adult↗
PubMed1996

[The retinal nerve fiber network layer in glaucoma. I. Introduction and methods].

In the retinal nerve fiber layer diffuse and localized defects can be seen in glaucoma. Photographs made with a green filter on black and white high contrast film allow to follow these alterations. This method will be used together with colour photographs for the statement of intra- and interobserver agreement.

Fluorescein Angiography↗
PubMed1994

[Ophthalmologic and psychophysiologic changes in patients in long-term dialysis treatment].

In 14 patients (7 men and 7 women), mean age 48 and 50 years resp. with chronic renal failure, having regular dialyzation treatment for more than 10 years (2 patients more than 20 years) the authors made ophthalmological and psychophysiological examinations in order to assess complications after prolonged dialysis. In three patients dialysis was discontinued while a graft was functional. In addition to known complications, calcification of the conjunctiva, osmotic cataract and retinal changes and changes of the optic disc the authors detected also changes of the visual field, contrast sensitivity and colour differentiation. They revealed changes of contrast differentiation in all spatial frequencies with a maximum in medium and upper frequencies. They revealed in more than 60% disorders of colour differentiation with a maximum in the blue-yellow and blue area of the spectrum. Ophthalmic complications the frequency of which is declining only rare by endanger the function of the eye.

Eye Diseases↗
PubMed1992

[Changes in the visual field after laser coagulation in type I diabetics].

The authors examined 41 eyes of 22 compensated type I diabetics 1 - 2 years after laser photocoagulation, using an automatic static perimeter Peritest. One fifth of the investigated patients had marked changes - DR20. The patients are not aware of the diminution of the visual field. Even the most extensive diminution of the visual field in this group did not restrict the ability to drive motor vehicles.

Adult↗
PubMed1992

[Treatment of chronic uveitis with long-term administration of penicillin].

The authors followed up a group of 20 patients with chronic uveitis (10 men and 10 women), mean age 36.5 years. Despite treatment of the foci, they suffered on average from seven relapses of the disease, frequently several times in the course of one year. From the anamnestic aspect there was a significantly high number of spells of tonsillitis, respiratory infections and arthralgia. Half the cases of uveitis, mainly anterior, were bilateral. The patients suffered from dysimmunoglobulinaemia with low values of FW, ASLO, Latex. HLA B 27 was positive in five subjects. After one-year of Pendepon or Penclen administration (in half the patients with NORG) 18 patients did not develop a relapse for a period of 2-3 years. The method is simple, cheap, easy to use in field practice, in particular in junior patients. The clinical effect of treatment justifies the use of this method as an alternative of intermittent immunosuppression.

Adult↗
PubMed1991

[Ocular changes in Gardner syndrome].

In hereditary adenomatosis of the large bowel (familial polyposis) extraintestinal manifestations of the disease are common: hyperostosis, dental anomalies, soft tissue tumours, desmoid tumours etc. Patients with marked extracolic signs are described as patients with Gardner's syndrome. Recently a further sign is described--foci of congenital hypertrophy of the pigmented retinal epithelium. The authors examined 22 patients with confirmed hereditary adenomatosis (Gardner's syndrome). The typical finding of pigmented foci on the fundus was recorded in 18 subjects (82%) incl. 9 subjects (50%) where the finding was bilateral. The authors examined also 25 children of these patients. In those a positive finding was recorded in 11 (44%). Ophthalmological examination can contribute in a significant way to detection of an asymptomatic subject with hereditary adenomatosis, in particular when seeking risk patients in an affected family. Evaluation of ophthalmological changes can also contribute to the solution of some special genetic problems of this disease.

Adolescent↗
PubMed1990

[Long-term results after implantation of silicone orbital implants].

In 1980-1988 at the Second Ophthalmological Clinic 78 enucleations of the bulbs with a orbital silicon implant were performed. The tolerance of the implant and the cosmetic result of the operation was evaluated in 53 adults and 5 children. The observation period varied between 6 months and 7 years. From the total number of 53 adults a very good cosmetic effect was achieved in 9 (17.1%), a good effect in 25 (47.1%), a satisfactory effect in 12 (22.6%) a poor effect in 2 (1.8%) patients. The implant was rejected in 5 (9.4%) of the cases, 4 implants within one month and one two years after enucleation. A very good cosmetic effect was observed in one (20%) child and a good effect also in one (20%). The implant was rejected in 3 (60%) children, 1, 4 and 20 months after operation. Rejection after 20 months was preceded by an inflammatory reaction in the area of the implant. Rejection of orbital silicon implants in adults was as a rule due to surgical complications or incorrect surgical technique. In the rejection of implants in young children the increased biological reaction of the child organism may be involved.

Adolescent↗
PubMed1989

[Is the prognosis of pars plana vitrectomy in diabetic retinopathy dependent on the general status of the diabetic?].

Results of pars plana vitrectomy (PPV) were compared in two groups of patients. The first group was formed from 105 eyes of 87 diabetics without clinical signs of the diabetic nephropathy or nephropathy without decrease of renal functions. The other group was formed from 64 eyes of 50 diabetics suffering from diabetic nephropathy in the stage of the renal insufficiency. In the first group PPV was successful during the mean observatory period of 26 months, in 59 from 105 eyes (56%) and the mean visual acuity was 0.12. In the second group PPV was successful, during the mean observatory period of 18 months, in 34 from 64 eyes (53%) and the mean visual acuity was 0.09. Number of the successfully treated PPV was steadily decreasing according to the prolonged period of the further observations, in both mentioned groups: from 85 (81%) after 3 months on 62 (41%) after the interval of 3 years. The mean visual acuity in both followed groups was, with respect to the length of observation, moderately increased. Diabetic nephropathy in the stage of the renal insufficiency was without negative effect on the prognosis of PPV in complicated diabetic retinopathy. The more advanced organ complications of diabetes were not evaluated as contraindications of PPV and the operation may significantly improve the quality of the life of an otherwise heavily ill diabetic patient.

Adult↗
PubMed1989

[Laser therapy of diabetic retinopathy in pregnancy].

During the regular follow-up of risk pregnancies in the Central Bohemian region, concentrated at the First Obstetric Clinic in Prague, the authors detected 34 women with retinopathies. In nine they performed panretinal photocoagulation by means of an argon laser and recorded favourable results. The authors consider early laser therapy of retinopathies in pregnant diabetics useful and essential. Advanced forms of diabetic retinopathy in pregnant women still remain a contraindication of pregnancy. Pregnancy in diabetic women is always a risk and it would be a mistake not to take this fact into account.

Diabetic Retinopathy↗