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Biomedical subjects

J Kovarsky

Publications and source records attributed to J Kovarsky.

At least 19 recordsLinked to original sources
PubMed1986

Bolus intramuscular methylprednisolone acetate as a therapeutic adjunct in rheumatoid arthritis.

Eighty adult patients with classical or definite rheumatoid arthritis were given 200 bolus injections of intramuscular methylprednisolone acetate (MPA) over four years. This was used strictly as a therapeutic adjunct for polyarticular flares (greater than or equal to 5 swollen joints), not as a singular form of long-term treatment. Good clinical responses, lasting an average of eight weeks, were obtained in the vast majority of patients. Severe toxicity was minimal. Postbolus responses to intravenous ACTH stimulation were measured in 12 patients. We believe that intramuscular bolus injections, used cautiously in carefully selected patients with rheumatoid arthritis, are relatively useful, convenient, inexpensive, and safe.

Activities of Daily Living↗
PubMed1984

Vertebral sarcoidosis: demonstration of bone involvement by computerized axial tomography.

We have reported a rare case of vertebral sarcoidosis, clinically manifested by myalgia and bone pain, and therapeutically responsive to glucocorticoid therapy. Although technetium polyphosphate bone scanning revealed diffuse uptake in the spinal column, conventional x-ray films were normal. Computerized axial tomography (CAT) of the lumbar spine revealed characteristic sclerotic-rimmed bone cysts at multiple levels. We believe this to be the first reported case of osseous sarcoidosis demonstrated by CAT scan in the face of normal conventional bone roentgenograms.

Adult↗
PubMed1983

Tuberculous sacroiliitis.

We have described an unusual case of tuberculous sacroiliitis associated with adrenal insufficiency, with details of radiologic studies and review of the literature concerning tuberculous sacroiliitis.

Female↗
PubMed1983

Intermediate-dose intramuscular methylprednisolone acetate in the treatment of rheumatic disease.

Treatment with a high-dose, intravenous bolus of methylprednisolone has been reported in numerous cases of rheumatic diseases. The optimal routes of administration, dosage, dosage interval, and other factors are unknown. This report describes uncontrolled clinical observations with a single dose of 320 mg of intramuscular methylprednisolone acetate in patients with rheumatic disease (12 with rheumatoid arthritis, 2 with spondyloarthropathy). This treatment may provide a useful therapeutic adjunct in selected clinical circumstances.

Adult↗