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J Krácmar

Publications and source records attributed to J Krácmar.

At least 19 recordsLinked to original sources

[UV-spectrophotometry in drug control. 47. Drug substances with chromophores and auxochromes in cyclic and tricyclic systems (benzodiazepine, dibenzoazepine and dibenzodiazepine)].

The results of a systematic examination of the UV/VIS spectra of 10 drug substances with chromophores and auxochromes in bicyclic and tricyclic systems (benzodiazepine, dibenzoazepine and dibenzodiazepine) are described. Influences of substituents and solvents on shifts of the E, K, B and R bands are discussed.

Benzodiazepines

[UV-spectrophotometry in drug control. 41. Drug substances with chromophores and auxochromes in monocyclic compounds (pyrazolone, pyrazolidine, pyridazine, pyrimidine and pyrazine) and bicyclic compounds (benzoxazole, imidazole, benzthiazole and indene)].

The results of a systematic examination of the spectra of 15 drug substances with chromophores and auxochromes in monocyclic (pyrazolone, pyrazolidin, pyridazine, pyrimidine and pyrazine) and bicyclic compounds (benzoxazol, imidazole, benzthiazole and indene) in the UV and visible range were evaluated. Influences of substituents and solvents on shifts of the E, K, B and R bands were discussed.

Benzothiazoles

[UV-spectrophotometry in drug control. 39. Spectrophotometric behavior of substances with chromophores and auxochromes in aliphatic chains, in saturated heterocyclics and the heterocyclic compounds: furan, imidazole, thiazole, thiadiazole and oxadiazole].

The spectra of 22 drug substances with chromophores and auxochromes in the aliphatic chain, in the saturated heterocyclus and in heterocyclic compounds (furan, imidazole, thiazole, thiadiazole and oxadiazole) underwent a systematic investigation and the results obtained were evaluated. Influences of substituents and solvents on shifts of the E, K, B and R bands were discussed.

Chemical Phenomena

[UV spectrophotometry in drug control. 31. Spectrophotometric behavior of drugs with dibenzo-p-thiazine chromophores].

The results of a systematic examination of the spectra of 34 drugs with dibenzo-p-thiazine chromophores in the ultraviolet and visible range were evaluated. The substances under study were subdivided into 10 different types corresponding to a different substitution in position 3 and in one case in position 5 of the phenothiazine ring system. All of these types are characterized by the bands E, K and B which are--with only a few exceptions--separated by well developed absorption minima.

Chemical Phenomena

[Ultra-violet spectrophotometry in drug control. Part 23: Conclusions from the spectrophotometric behaviour of drugs with pyridine, naphthalene, quinoline and isoquinoline chromophores (author's transl)].

The results from a systematic study of drugs with pyridine, naphthalene, quinoline and isoquinoline chromophores are evaluated and condensed into conclusions. In addition to previously reported findings, the ultra-violet and visible spectra of a further nine drugs containing the mentioned chromophores are presented.

Isoquinolines