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Biomedical subjects

J Kraft-Kinz

Publications and source records attributed to J Kraft-Kinz.

At least 19 recordsLinked to original sources
PubMed1993

Twenty-four years' implant duration of the aortic Starr-Edwards Silastic ball prosthesis: a valve of the past?

Six years after the first aortic valve replacement with the Starr-Edwards Silastic ball prosthesis at Oregon Health Sciences University, the model 1260 was implanted in a 44-year-old patient at our department. During 24 years no signs of dysfunction, thromboembolism, thrombosis, periprosthetic leaks or hemolysis were observed. Material test showed no signs of fatigue. The dimension of the Silastic poppet was found to be one millimeter less than the original specifications of these poppets and there were some lipid infiltrations. Functionally the poppet was found to be nonvariant. Histologic findings detected focal hyalinization and giant cells without signs of acute inflammation or ulceration. With regard to its reliability and durability, the Starr-Edwards valve prosthesis should not be viewed with disfavor.

Adult↗
PubMed1987

[Endoscopic evaluation of a retard cimetidine preparation with reference to its effect in stomach and duodenal ulcer. A comparative study with a non-retard cimetidine preparation].

With the development of this new galenic retard administration, we found in conclusion a significant longer action interval. A dose increase, similar to non retard administrations was on no account necessary. The new drug, Cimetidine retard, offers accordingly the opportunity of full utilization of the offered pharmacologic effective substance in combination with low dose administration and poor side effects.

Cimetidine↗
PubMed1985

[10 years of endoscopy at the University Department of Surgery in Graz].

The results of the endoscopies carried out from 1973 to 1983 at our hospital are reported (6947 gastroscopies, 2189 colonoscopies). Gastroscopic aftercare following gastric resection for benign gastric disorders and after partial gastrectomy for carcinoma is discussed. The results of the use of laser in emergency endoscopies are presented (731 patients with 827 bleedings lesions). By implementation of laser there was a remarkable reduction in the rate of immediate and early operation and in early mortality in cases of gastrointestinal bleeding. The results of 244 endoscopic polypectomies are reported.

Aftercare↗
PubMed1985

[Initial results of hyperthermia in palliative therapy of cancers in the ENT area].

Preliminary results of an interdisciplinary study, conducted to investigate the efficacy of combined local hyperthermia and radiation/chemotherapy on carcinoma of head and neck, are reported. Upto now, eleven patients with recurrent squamous cell carcinoma of head and neck were treated, all of them had loco-regional recurrence, and 2 distant metastases in addition. 7 patients were pretreated by surgery and radiotherapy, 4 by radiotherapy only, and 6 by chemotherapy. Microwave-induced low-dose local hyperthermia was combined with radiotherapy (telecobalt 1100-2400 rad) 6 cases (group A) and with chemotherapy (bleomycin and cis-platin/bleomycin) in 5 patients (group B). Intratumoural temperatures between 43 and 45 degrees C were achieved for at least 30 minutes. The loco-regional efficacy of hyperthermia was assessed. 10/11 patients with 13 tumours could be evaluated, Group A: 3 CR, 4 PR, Group B: 1 PR, 4 MR and 1 NC.

Adult↗
PubMed1983

[Aortic valve replacement in cardioplegic heart arrest].

The St. Thomas cardioplegic solution was introduced in our clinic in January, 1980. Before, aortic valve replacements were carried out using cold ischaemic cardiac arrest as myocardial preservation technique. In 62 aortic valve replacements performed since January 1980, there was no hospital mortality. Moreover, there were fewer intraoperative and postoperative complications. Intraoperative serum potassium was not essentially elevated after cardioplegic perfusion of the heart, although most of the cardioplegic effluate passed into the extracorporeal circulation. Postoperative serum-creatinphosphokinase levels were significantly higher after cold ischaemic arrest than after cardioplegia.

Aortic Valve↗
PubMed1983

[Resorbable suture material in cardiovascular surgery?].

The examination of a new, fully resorbable suture material (polydioxanon) in case of artery sutures is reported. Smaller tissue reactions are found than in all suture materials examined. Exceptional long durability for fully resorbable suture material seems in case of anastomoses in vessels very usefull.

Animals↗
PubMed1983

[Shunt malfunction due to a Blalock-Taussig anastomosis of the pulmonary vein].

In two of 81 patients in whom a Blalock-Taussig shunt was created due to pulmonary atresia, the anastomosis was inadvertently placed on the pulmonary vein. The first case was a newborn with mirror-image dextrocardia, pulmonary valve atresia and a high ventricular septal defect. Subsequent to a Rashkind maneuver and treatment with prostaglandins, at the age of eleven days the shunt procedure was performed. Right sided pulmonary edema developed twelve hours after surgery and the infant died on the second postoperative day. Anastomosis of the shunt to the right pulmonary vein was revealed at autopsy. The second case was a six year-old boy admitted for corrective surgery with pulmonary valve atresia, main pulmonary artery atresia, large ventricular septal defect and patent ductus arteriosus. Because of additional systemic-pulmonary collaterals, the larger collaterals were ligated and the Blalock-Taussig shunt was carried out using a Goretex prosthesis. Nine months postoperatively, at follow-up cardiac catheterization, the ill-directed shunt was diagnosed and subsequently revised. The onset of ipsilateral pulmonary edema and increasing signs of congestive heart failure after surgical creation of a Blalock-Taussig shunt as well as the persistence of lowered oxygen partial pressure, cyanosis and poor general health, should alert the attending physician to rule out the rare complication of anastomosis to the pulmonary vein.

Arteriovenous Shunt, Surgical↗
PubMed1982

[Diagnosis and therapy of cancer of the large intestine (author's transl)].

A review is presented of the cases treated in this department between 1944 and 1979. Radical surgery was carried out in 388 patients out of 746, whereby the majority of patients were in the older age brackets. Paralytic ileus was present in about 25% of cases and three-stage procedure was, thus, required in the management of these patients. The mortality decreased from 16.6% to 2.1%. The 5-year survival rate was on the lower limits of the range quoted in the literature. Aetiology diagnosis and preoperative management is discussed.

Aged↗
PubMed1982

[Role of the pericardium in acute volume overload].

The function of the pericardium in acute volume overloading may be defined as protection against ventriculo-atrial regurgitation at high filling pressures, limiting transmural pressures and, therefore, protecting against ventricular distension as well as supporting the filling of the ventricles by suction in the systolic contraction. Thus, it may be important to close the open pericardium carefully after open heart surgery. Pericardial drainage should prevent cardiac tamponade.

Animals↗
PubMed1980

[Treatment of carcinoma of the rectum (author's transl)].

620 patients with carcinoma of the rectum treated in the years 1944 to 1966 are compared with 301 patients treated in the years 1967 to 1978. There was an increase of the operations alltogether and of the curative operations in particular. In the same space of time the mortality was reduced remarkably. The 5-year-survival time after resections was 38%, after abdomino perineal excision 48%.

Adult↗
PubMed1980

[Surgical treatment of congenital heart disease in infants without use of extracorporeal circulation (author's transl)].

Between 1970 and 1978 135 infants with congenital malformations underwent operations due to congestive heart failure, progressive pulmonary hypertension, and severe cyanosis. Of them, 63% were acyanotic; 68% of all operations became necessary during the first 6 months of life. The late mortality rate was 5% and the hospital mortality rate 17%. A remarkably higher operative risk was found during the first 6 months of life. Ligation of patent ductus arteriosus as the most common lesion was done with a mortality rate of 2.5% which is comparable to the risk of late repair in childhood. Pulmonary artery banding could be performed in all acyanotic malformations with a mortality rate of 17% and of 12.5% in isolated VSD (including debanding and VSD closure in several cases). Coarctation of the aorta was corrected with a overall mortality rate of 26%. Because of a recurrence rate of 20%, the authors think that operations are only indicated in symptomatic cases of coarctation. In complex cyanotic malformations, a higher operative risk was observed in both pulmonary artery banding (38%) and shunt operations (44%). If surgical treatment is necessary, the earlier, the better.

Age Factors↗