Biomedical subjects

J Krempa

Publications and source records attributed to J Krempa.

3 recordsLinked to original sources

PubMed1981

Contrast enhancement in the postoperative brain.

Contrast enhancement simulating an abscess or residual tumor has been described in postoperative cranial computed tomography (CT) scans. This study was undertaken to determine the cause of this contrast enhancement by using canine brain as an experimental model. Sequential CT scanning was performed with and without contrast enhancement following partial resection of the right hemisphere, and the CT findings were correlated with the histological changes. Findings indicate that enhancement of the surgical margin is related both temporally and spatially to the neovascularity following surgery. The ring-like enhancement around the surgical margin is seen best at two to four weeks after surgery, and may simulate an abscess. However, edema seen around an abscess in adjacent brain is absent or minimal in the case of postoperative enhancement during this period, and this feature should help differentiate these entities.

Animals↗

PubMed1981

Computed tomography of the perineum.

The value of computed tomography (CT) in the assessment of pelvic malignancy is well established. However, the importance of scanning caudad to the symphysis pubis to include the perineum has not been emphasized. The CT anatomy of the perineum in the transverse, coronal, and sagittal planes planes in normal subjects and in cadaver specimens is reviewed, and experience in 22 patients with pelviperineal pathology is reported. Malignancies in 16 patients were of the cervix (seven), vulva (six), vagina (two), and a recurrent mesenchymoma (one). Six patients had abscesses; one of these had cellulitis and skin ulcers. CT clearly depicts the perineal anatomy and is the imaging method of choice for the evaluation of malignancies and abscesses originating from or extending into this anatomic space. failure to include the perineum in the CT scanning of the pelvis will result in underestimation of disease extent. Multiplanar CT display of pelviperineal anatomy has great potential application in clinical work when high resolution coronal and sagittal reconstruction of transverse scans becomes available.

Adult↗

PubMed1980

Postoperative computed tomographic changes in the brain: an experimental study.

Contrast enhancement in the brain on computed tomography (CT) after an operation was studied in otherwise healthy dogs to evaluate the stages of enhancement caused by surgical changes. Serial CT scanning was done with and without contrast enhancement following a partial posterior parietal lobectomy. Pathologic correlation was obtained. Contrast enhancement occurred as early as one week, with peak incidence occurring between two and six weeks. Enhancement was diminishing or absent by the eight week after operation. Separate components of enhancement secondary to breakdown of the blood-brain barrier and to vascular granulation tissue may be distinguishable.

Animals↗