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J Krenzien

Publications and source records attributed to J Krenzien.

11 recordsLinked to original sources

[Perforated gastroduodenal ulcer. I. postoperative mortality and late results following simple suturing].

Following the introduction of H2-blockers in the treatment of gastroduodenal ulcer disease, there has not been a change in the incidence of perforated peptic ulcer. By the diagnosis of perforated peptic ulcer the indication for an emergency operation is shown in generally. The postoperative mortality amount now as before 10% and the ulcer relapse rate behave less or more high, dependent on operative procedures, which optical choice is open. Therefore the perforated gastroduodenal ulcer has not lost any actuality. The following paper takes into account the informations of 245 patients from 1970 to 1988, which perforation of peptic ulcer were treated only with simple suture. The collection of data was retrospective till 1985 and since then prospective. Beside analysis of postoperative mortality, reasons of death, complications during healing and preoperative false diagnosis we have done a follow up of operated patients till 1987 (n = 232). On the basis of the results a statement was given for the therapeutical management of ulcer perforations.

Adolescent

[Surgical risk in old age. Prospective evaluation of a prognosis index].

A prognostic index of octogenarians was calculated by a critical retrospective analysis of our results of the outcome after operations. In the years 1986-1988 this index was prospective validated at 381 patients over 80 years old. The accuracy was 85%. The other quality parameter (sensitivity, specificity, negative and positive predictive values) of the decision point of our prognostic model reached good or very good values too. This results showed the possibility of application for the recommended prognostic index. In the last three years the postoperative mortality has fallen essential in general surgery. At present the mortality estimate 20% for emergency and elective operations for the whole hospital stay of the patients. The direct clinical utility of risk analyses to work out prognostically statements was proved by this study.

Aged

[Scoring systems for severe intra-abdominal infections].

In the following paper a review is given on the development of scoring-systems of severe intraabdominal infections till now. After a critical reflection on various systems a heuristic assessment is shown in the summing-up about their possible utility in the future. At present the APACHE II index, the sepsis score by Elebute and Stoner and the Mannheim peritonitis index meet practically requirements for good scores by different revising questions.

Female

[The application of scoring systems for surgical intensive care patients].

In a prospective study above five months 8 classification-systems were examined to allow a grading of the severity of diseases in surgically intensive patients (n = 44). The aim was to check their practicability in clinical handling and their application as a parameter of course of critical ill patients. In spite of the relative small number of patients, in the result came the strong and weak points of scoring-systems for expression. For surgically intensive patients are recommended the APACHE-II index and the sepsis-score by Elebute and Stoner for cases with severe infections.

Adolescent

[Perforated gastroduodenal ulcer. II. Risk analysis in the prognostic evaluation of the postoperative course].

The data of 245 patients of our clinic, which perforation was treated with simple suture, were analysed by uni- and multivariate statistics to estimate risk factors. The aim was to predict the postoperative outcome. In a first step univariate test methods gave some orientation of the relevance of the factors. There was a highly significant correlation of age, preoperative shock, medical illnesses, time interval perforation-operation and clinical diagnosis to postoperative mortality. In a second step a multivariate decision model was used to calculate a prognostic index of the outcome after operation of perforated peptic ulcer. The index was tested in a cohort study. The results of validation were good for all quality parameters, so that the index allows a relatively safer statement about the so-called risk patients.--The prognostic problems of perforated gastroduodenal ulcer, including diagnosis, are also represented with graphic figures in the form of decision trees.

Adolescent

[Sigmoid diverticulitis].

Colonic diverticulitis has become a relatively frequent disease, with the sigma being affected by up to 95 per cent of all cases. Its clinical relevance has proved to depend on the prognosis of life-threatening diverticulitis complications. Sixty patients who had received surgical treatment at the Surgical Department of Potsdam District Hospital were analysed. That analysis together with evaluation of literature has been used for therapeutic recommendations. For cases of sigmoid diverticulitis early elective intervention is advised. The method of Henri Hartmann is considered an effective approach to diffuse peritonitis.

Abscess

[Surgical risk in the elderly].

Analyses in the context of risk research prove to be clearly relevant to clinical practice, when it comes to diseases with increased postoperative morbidity and lethality. Results of surgical therapy are not in all cases satisfactory, if patients in advanced age are involved. A critical appraisal of this problem has continued to be necessary. Univariate and multivariate statistical techniques were used for an analysis of the data recorded from 481 patients above 80 years of age (1979 through 1985). A prognostic index is proposed as a result of the analysis.

Aged

[Endometriosis of the large intestine].

Extragenitally localized endometriosis with necessity of treatment is very rare. By means of case reports topical problems of symptomatology, diagnostics and therapy of endometriosis intestini have been discussed from surgical point of view.

Adult