Biomedical subjects
Publications and source records attributed to J Kubinyi.
The paper is submitted as one of the recommendations for diagnostic and therapeutic care in nuclear medicine meant in particular for the clinical need of physicians indication treatment of thyroid carcinoma with iodide. The author presents a brief review of principles, indications, the procedure proper, clinical interpretation and possible risks and contraindications, incl. the clinical and socioeconomic impact.
The paper is presented as one of recommendations of diagnostic and therapeutic care in the field of nuclear medicine intended especially for the clinical needs of physicians indicating palliative treatment of metastases into bones using radiopharmaceuticals. It provides a brief review of principles, indications, the very performance of interventions, clinical interpretations, possible risks and contraindications including the clinical and social-economic meaning.
Autologous polymorphonuclear leucocytes are injected after separation and labelling with 111In oxine to the patient with a suspect inflammatory process and after 24 hours their localization is assessed by standard scintigraphic examination by a scintillation camera. The authors examined in a prospective investigation 33 patients--the sensitivity of the method was in that group 80%, the specificity 100%, the diagnostic accuracy 94%. The authors discuss the possibilities of application of the method in intraperitoneal abscesses and in some inflammations with another localization. They evaluate the contribution of the method in the diagnosis of inflammatory processes, as compared with the possibilities offered by computed tomography and ultrasound.
In the course of the analysis of the results of 175 cerclage-operations carried out during the last 5 years, the authors intended to answer the question: whether the operation is reasonable on the basis of a prophylactic indication. As indication of this kind has been considered for example the following: when in the case-history of the patient one or more spontaneous abortions have occured after the third month of gravidity--with insufficient symptoms, when the mother's birth was a full-term confinement after cerclage-operation, finally, when the insufficiency of the cervical os had been diagnosed before getting pregnant. At symptoms of incipient abortion the aim of the medical treatment was therapeutic. The prophylactic operation was performed between the 16-18th week of the pregnancy, while the therapeutic one between the 20th and 30th week. In the first group 97,2 per cent was the rate of the viable children, while in the second one: 67,2 per cent. The well-foundedness of the prophylactic indication is proved by the fact that the number of full-term confinements has been quinetupled, compared with the pre-operation state. In our opinion in case of typical anamnesis the cerclage-operation is to be performed earlier than in the practice up till now, before opening the cervical os, and the infection of the amnion.
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