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J Kwanjana

Publications and source records attributed to J Kwanjana.

7 recordsLinked to original sources

Providing HIV care for tuberculosis patients in sub-Saharan Africa.

Human immunodeficiency virus (HIV)/acquired immunedeficiency syndrome (AIDS) and tuberculosis (TB) cause an immense burden of disease in sub-Saharan Africa. A large amount of knowledge has been gathered in the last 15 years about the negative impact that HIV has on TB control, both at a programme level and at the level of the individual patient. Equally, interventions that are known to benefit patients have been tested and piloted, and these form important components of international TB-HIV guidelines, a TB-HIV strategic framework and an interim policy on TB-HIV coordination. Unfortunately, in sub-Saharan Africa there is little evidence that these interventions are being implemented on the ground, and one of the reasons for this paralysis is that the operational details are not well developed. This paper takes the three important HIV interventions of HIV testing and counselling, cotrimoxazole preventive treatment and antiretroviral treatment, and discusses some of the practical details of on-the-ground implementation. We hope that this will generate discussion, but above all, the impetus to start delivering services to patients.

Africa South of the Sahara↗

Risk of infection with Mycobacterium tuberculosis in Malawi: national tuberculin survey 1994.

OBJECTIVE: To estimate the annual risk of tuberculosis infection among schoolchildren in Malawi. METHODS: A school survey was conducted in twelve randomly selected districts in Malawi. Children in standard 1-4 and aged 6-11 years were eligible. Tuberculin skin testing was performed according to World Health Organization/International Union Against Tuberculosis and Lung Disease guidelines. RESULTS: Of the 17123 eligible children, 80% were tested. Of those tested 79% were read. The prevalence of infection according to various criteria was 9-12% in children without bacille Calmette-Guerin (BCG) scar. The prevalence of reactions of 10 mm or more was lower in girls than in boys, increased with age, and was higher in those with than in those without BCG scar. The annual risk of infection was estimated to be within the range 0.6-1.4%. CONCLUSION: Annual risk of infection in Malawi was in the order of 1%. This study is expected to provide valuable baseline information for an assessment of the impact of human immunodeficiency virus (HIV) on tuberculosis transmission in Malawi.

Age Distribution↗