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Biomedical subjects

J L Arredondo

Publications and source records attributed to J L Arredondo.

18 recordsLinked to original sources
PubMed1998

[Microbial etiology of mild and moderate pelvic inflammatory disease].

Pelvic inflammatory disease (PID) is one of the most severe complications of sexually transmitted disease (STD). It can be due to the ascending of normal endogenous microorganisms of the female genital tract or the infection by microorganisms related to STD as Chlamydia trachomatis and Neisseria gonorrhoeae. PID leads to serious gynecoobstetric consequences as infertility and ectopic pregnancy. Clinicians face the problem of knowing the ethiology of PID in order to treat appropriatly patients with this clinical diagnosis. So that, this work pretends to establish what kind of microorganisms are implicated in PID. A proper isolation and identification of microorganisms achieved by culture of lower genital tract samples from endocervix, endometrium and peritoneal fluid, leading to a betther, specific and proper treatment of this disease.

Anti-Bacterial Agents↗
PubMed1997

Oral clindamycin and ciprofloxacin versus intramuscular ceftriaxone and oral doxycycline in the treatment of mild-to-moderate pelvic inflammatory disease in outpatients.

This multicenter, prospective, double-blind study compared the safety and efficacy of clindamycin and ciprofloxacin versus ceftriaxone and doxycycline in the treatment of outpatients with mild to moderate pelvic inflammatory disease (PID) diagnosed by laparoscopy. Samples taken from the endocervix, endometrium, and abdominal cavity before treatment and from the endocervix after treatment were cultured for aerobes, anaerobes, Neisseria gonorrhoeae, and Chlamydia trachomatis. Of the 138 patients enrolled, 131 were evaluable for efficacy. The most prevalent bacteria were streptococci, staphylococci, and Escherichia coli (among aerobes) and Bacteroides species and peptostreptococci (among anaerobes). N. gonorrhoeae was present in 2% (3) of the 131 evaluable patients, and C. trachomatis was in 11% (15). The clinical cure rate was 97% (65 of 67) in the clindamycin and ciprofloxacin group and 95% (61 of 64) in the ceftriaxone and doxycycline group. Side effects were similar in both groups. In conclusion, the two regimens for the outpatient treatment of mild to moderate PID were similarly effective and safe.

Administration, Oral↗
PubMed1995

[Evidence of antimicrobial activity of the follicular fluid: an evaluation and analytical study of samples obtained in an assisted reproduction program].

Due to lack of evidence of infection in patients for ovarian punction for ovular capture, the hypothesis of possible antibacterial action that could exist in follicular fluid, was evaluated. One hundred and ten samples of such fluid, were taken for antibacterial analysis, 37 of which, were studied, as they were the clearest ones and not contaminated. Such samples were obtained from hyperstimulated patients, ready for ovular capture through vagina by ultrasonographic guide. A bacterial inoculum, was prepared, in order to evaluate antimicrobial activity of follicular fluid against E. coli, P. aeruginosa, S. agalactiae, L. monocytogenes and C. albicans. Counting of bacterial colonies, at 2, 4, 6, 12 and 24 hours. Results summary shows bacteriostatic activity in all studied colonies, and E. coli and S. agalactiae seem to be the most sensitive, followed by P. aeruginosa, S. aureus and L. monocytogenes; and still present in C. albicans. It is concluded that follicular fluid has an antibacterial action, probably selective; and that keeping this research line will confirm this finding, and possibly will determine the concerned factors.

Bacteria↗
PubMed1993

Gastric heterotopic mucosa in the rectum with Helicobacter pylori-like organisms: a rare cause of rectal bleeding.

We report the case of a 9-year-old boy who presented with chronic rectal bleeding. On proctosigmoidoscopy, a polypoid elevation in the rectal ampulla measuring 5 x 3 cm was found. Biopsies were reported to show gastric mucosa. The Giemsa stain showed Helicobacter pylori-like organisms. Including our patient, there are now 30 similar cases reported in the medical literature. The usual manifestations of this rare entity are chronic bleeding and rectal pain. In one-half of cases there is chronic rectal ulceration. The recommended treatment is transanal surgical resection unless there is rectal peptic ulceration. H2 receptor blockers are then advised. Surgical excision is carried out after healing has taken place.

Child↗
PubMed1993

Identification and partial characterization of an immunoglobulin A protease associated with human sperm.

The ability of human sperm to evade local humoral immune response at the female genital tract has received little attention. As some microorganisms inactivate secretory immunoglobulin A (S-IgA) by enzymatic degradation as a part of their pathogenic mechanism, we decided to test the hypothesis that there is an IgA protease in human semen that helps sperm to progress through the cervix uteri. Incubation of different semen fractions in the presence of S-IgA revealed IgA protease activity associated with raw semen or sperm but not with seminal plasma; raw semen and sperm produced two split products of 66 kDa and 45 kDa, respectively, in SDS-PAGE. The enzymatic activity was blocked with EDTA. IgG and IgM were not digested under the same experimental conditions. Degradation of S-IgA by an IgA protease on the sperm surface may be among the mechanisms present in semen that enable sperm to evade an immune response in the female genital tract.

Female↗
PubMed1993

[Hepatitis C during puerperium].

Screening of donor blood for hepatitis B led to recognition that most cases of post-transfusion hepatitis were due to an agent known as non-A, non-B. Until recently the causative agent for non-A, non-B hepatitis was identified, being denominated hepatitis C virus. It is estimated that one-half of patient with hepatitis C develop chronic liver disease, and 20% of this will develop cirrhosis. We describe a patient who due to obstetric complications received blood transfusion and during puerperium developed an icteric syndrome which was identified as C hepatitis. We review the diagnostic methodology, clinical characteristics, evolution and preventive measures of the C hepatitis.

Adult↗
PubMed1988

Results of treatment of uncomplicated urogenital gonorrhoea with enoxacin compared with ceftriaxone.

The increasing incidence of penicillinase producing Neissreria gonorrhoeae (PPNG) and chromosomally-mediated resistant N. gonorrhoeae (CMRNG) has generated a need for therapy other than penicillin. PPNG constitutes about 30% of the circulating strains of gonococci in the high risk population in Mexico City. The object of the present study was to compare the safety and efficacy of single-dose treatment with either oral enoxacin (400 mg tablet) or intramuscular ceftriaxone (250 mg injection), for the treatment of acute uncomplicated gonococcal urethritis in men, caused by N. gonorrhoeae, including both PPNG and non-PPNG strains. Of the 93 men with uncomplicated gonorrhoea entered into a study, randomly assigned to receive ceftriaxone or enoxacin, 80 completed it. Infections were initially diagnosed by Gram-stained smears of urethral exudate and subsequently confirmed for isolation of N. gonorrhoeae. Chlamydia trachomatis was confirmed by direct immunofluorescence. About 30% of the strains of gonococci were PPNG and 1% were CMRNG. C. trachomatis was coexisting with N. gonorrhoeae in about 25% of the patients and remain positive after treatment. In the study presented, a single dose of either enoxacin or ceftriaxone was highly active against both PPNG or CMRNG. One single dose was enough to achieve a 100% cure rate. There was no difference between the two treatment groups. Thus either regimen has proved to be a useful alternative to the present-day treatment of uncomplicated gonococcal infections.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMedDate not supplied

[Pleuropulmonary lesions due to Haemophilus influenzae].

Empyema due to Hemophilus influenzae has been reported only rarely. This report describes the cases of ten children with empyema due to this organism. Diagnosis was made through growth of the organism in pure culture from pleural effusion. H. influenzae empyema may occur in older children as well as in infants and, in contrast to certain other infections with this organism, empyema due to H. influenzae may be more common than is generally suspected.

Ampicillin↗
PubMedDate not supplied

[Complications of chickenpox].

A patient with typical varicella (chickenpox) developed several complications: nephrotic syndrome following glomerulonephritis, trombocytopenic purpura, gastrointestinal bleeding, disseminated intravascular coagulation, encephalitis and bronchopneumonia. The course was satisfactory having been given antibiotics, heparin and peritoneal dialysis. Recovery was 100%.

Anti-Bacterial Agents↗
PubMedDate not supplied

[Treatment of chronic osteomyelitis].

Levels of Cephaloridine and Cefazoline were measured in serum, pus and bone in 20 patients with chronic osteomyelitis and the efficiency of these drugs in the treatment of osteomyelitis was evaluated.

Adolescent↗