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Biomedical subjects

J L Bens

Publications and source records attributed to J L Bens.

At least 19 recordsLinked to original sources

[Blood gas and acid-base changes and rhythmologic tolerance of acetate and bicarbonate hemodialysis using a standard dialyser with high sodium and control of ultrafiltration].

In order to demonstrate a possible superiority of bicarbonate dialysis (HDB) over acetate dialysis (HDA) in conditions of standard dialysis (4 hours on a 1 m2 cuprophan dialyser) but with a bath rich in sodium (143 mEq/l) and control of ultrafiltration, we have compared 2 sequences of 3 runs of HDA and HDB with these conditions in 8 patients as regards their acido-basic and cardiologic parameters (continuous monitoring of ECG by Holter, regular measurement of blood pressure). Acid base balance study in AHD led to the distinction of 2 groups according to wether their plasma bicarbonate increased or decreased during the run. Rythmological tolerance was the same in BHD and AHD, wether all patients or both groups were considered. Heart rate was however slightly but significantly higher during AHD than during BHD, in the patients whose plasma bicarbonate decreased. In conclusion, the benefit of HDB is not remarkable when HDA is performed not only in standard conditions but also with a bath rich in sodium and with control of ultrafiltration.

Acetates↗

[Value of hemodynamic exploration under exercise in chronic bronchitis].

Pulmonary haemodynamics was studied in the course of a calibrated exercise test on an ergometric cycle in 55 patients with chronic obstructive respiratory disease. Three groups of patients could be distinguished: absent pulmonary artery hypertension, both at rest and on exercise (group I), pulmonary artery hypertension on effort only (group II), permanent pulmonary hypertension, both on effort and at rest (group III). If adaptation of the cardiac output to exercise was identical in three groups and appeared to be normal, the relationship between pulmonary artery pressure and flow differed clearly from one group to another. Elements of orientation make it possible to foresee this latent pulmonary artery hypertension on the basis of rest gazometry and simple spirography data. The prognostic and aetiologic significations were discussed.

Bronchitis↗

[Effects of post-infarct physical training on physical fitness and cardio-circulatory adaptation to effort].

In fifteen patients recovering from a myocardial infarction dating of at least three months, examined at rest or during a submaximal exercise, various circulatory (cardiac rate, blood pressure, cardiac output...) and ventricular parameters (oxygen consumption, ventilation per minute) both before and after a program of physical training for a period of six to eight weeks. The benefit of readaptation was judged on the increased work capacity (VO2max increase of 24.6%) and the improvement of cardio-circulatory adaptation during a submaximal exercise: reduction of the cardiac rate by 11%, of Katz's index by 12.6%, of the cardiac output by 5.8% and of the left ventricular work by 8.8%. This cardiac thrift at the origin of the increase of physical aptitude is essentially due to a better peripheral circulation adaptation to exercise, as indicated by the increased oxygen arterio-ventout difference by 11.4%.

Adult↗

[Value of the exercise test in the functional evaluation of non-coronary cardiac patients].

72 cardiac patients underwent an exercise test on the bicycle ergometer, with direct measurement of the oxygen consumption (VO2). These results are compared with those of 55 healthy subjects undergoing the same test. The amount of handicap varied with the nature of the cardiac lesion, being 39% for the mitral and cardiomyopathy groups, 31% for those with both mitral and aortic valve disease, 27% for the aortic valve group, and 25% for those with congenital abnormalities. The linear relationship between Watts and VO2 was reproduced both in the healthy and cardiac subjects, which allows us to calculate the value of VO2 under conditions of load for more than 3 minutes during a standardized exercise test.

Adult↗