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Biomedical subjects

J L Bezanilla Regato

Publications and source records attributed to J L Bezanilla Regato.

At least 19 recordsLinked to original sources
PubMed1992

[Nutritional study of children with oncologic diseases].

From October 1989 to June 1990 we have evaluated at diagnosis and after six months of treatment the nutritional status of 21 oncologic patients younger than 14 years. At diagnosis, 14% of the children showed slight malnutrition on anthropometric evaluation, although there were biochemical data of protein malnutrition in 47% of the cases. Children with abnormal anthropometric measurements and those with a high risk of becoming malnourished (infants with advanced abdominal diseases) were given dietary supplements. In the follow-up evaluation, 90% of the patients showed normal somatic indexes and 76% showed recuperation in their protein values. The recovery of the nutritional status was most important in the group of patients with Acute Lymphoblastic Leukemia.

Adolescent↗
PubMed1991

[Second solid tumors in childhood. Review based on three cases].

As children with cancer survive longer, the incidence of second malignant neoplasms has increased considerably. We describe here three cases of second solid tumors after 12, 8 and 2 years of initial diagnosis of cancer: one osteosarcoma of left maxilla in a previously treated child with bilateral retinoblastoma, a temporal astrocytoma associated with acute lymphoblastic leukemia and a glioblastoma multiforme in a girl with neurofibromatosis de Von Recklinghausen, after Non Hodgkin lymphoma, respectively. We review the literature about the influence of genetic, immunologic and therapeutic factors involved in the appearance of these second tumors.

Astrocytoma↗
PubMed1990

[Familial hemophagocytic lymphohistiocytosis: survival of a case treated by polychemotherapy].

A case of familial hemophagocytic limphohistiocytosis (FHLH) is presented in a 16 months old infant, with clinical picture of prolonged fever, cutaneous purpura, generalized lymphadenopathy and progressive hepatosplenomegaly and laboratory of severe pancytopenia, hypofibrinogenemia and hypertriglyceridemia, with elevation of the pre-beta fraction in the lipidogram, all this compatible with this disease. She also showed bone marrow and ganglionar biopsy infiltrated by histiocytic cells with hemophagocytosis. The patient received chemotherapy with cycles VP-16, vincristine (VCR) and intrathecal methotrexate (MTX), alternating every two-three weeks with VACP, during one year, with resolution of clinical and laboratory parameters after two months of this treatment without relapses. The survival from diagnosis is 39 months.

Drug Therapy, Combination↗
PubMed1989

[Simultaneous bilateral Wilms tumor].

Bilaterality is uncommon in Wilms' tumor, being present in 4% to 8% of the cases. Definite progress has been made in the treatment with marked improvement in prognosis. The recent trend toward more conservative sugery, preoperative chemotherapy an avoidance of high-dose radiation therapy has yielded good results. This is confirmed in our two cases with synchronous tumors.

Adolescent↗
PubMed1976

[Acute lymphoblastic leukemia: treatment results in 27 children (author's transl)].

Therapeutic protocol and treatment results of 27 children with acute lymphoblastic leukemia are described. A remission rate of 88 per 100 was obtained. Fourteen children are living. Five of those followed for two or more years are living (35 per 100). The prophylaxis of leukemic meningitis was done with intrathecal Methotrexate. Only one child treated in this manner developed leukemic meningitis. Infection was the most frequent cause of death.

Child↗