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Biomedical subjects

J L Billard

Publications and source records attributed to J L Billard.

11 recordsLinked to original sources

Accuracy assessment for three fiberoptic pulmonary artery catheters for SvO2 monitoring.

OBJECTIVE: To compare values of SvO2 obtained by reflectance spectrophotometry continuous monitoring with those obtained from blood samples measurements by transmission spectrophotometry (Co-Oximetry). DESIGN: Values of SvO2 recorded by three pulmonary artery catheters for continuous monitoring, SAT1, SAT2 and Oximetrix3 (OX3), were compared in a prospective manner to those measured on blood samples by a Co-Oximeter, using the statistical analysis of Bland and Altman. SETTING: Adult intensive care unit in an University Hospital. PATIENTS: 37 patients admitted for acute respiratory failure and/or shock who required hemodynamic monitoring. MAIN RESULTS: The bias (average under- or overestimation) was small for all comparative measurements: +1.3, -0.2 and +1.0 sat% for SAT1, SAT2 and OX3, respectively. However, limits of agreement were only acceptable for SAT2 (-8.3 to +7.9 sat%) and OX3 (-6.7 to +8.6 sat%), but not for SAT1 (-23.3 to +25.9 sat%). No significant drift during 24 h was found with the three catheters. However, in vitro calibration was only found acceptable for SAT2 and OX3. The results were not influenced by the numbers of wavelengths of the device (2 for SAT1 and SAT2, and 3 for OX3) nor did they correlate with any of the hemodynamic and biochemical variables tested. CONCLUSION: For usual monitoring in the ICU, SAT2 and OX3, gave SvO2 values which are in acceptable agreement with SvO2 measured on blood samples by Co-Oximetry.

Aged↗

[Traumatic rupture of the aorta diagnosed by transesophageal echocardiography. Apropos of a case and review of the literature].

The authors report the case of subadventitial rupture of the isthmus of the aorta due to trauma, diagnosed by transoesophageal echocardiography. The role of transoesophageal echocardiography compared with conventional diagnostic techniques is discussed. This method of investigation is a very good diagnostic tool in cases of closed trauma of the thorax.

Accidents, Traffic↗

[Colonic perforation after renal transplantation].

Among surgical complications following kidney transplantation, the colonic perforation should be known. We reported a fatal case of perforation occurring on a colonic diverticulosis in the first month week post-transplantation. We emphasized on the difficulty to assess the diagnosis.

Aged↗

[Cholestatic hepatitis caused by ketoconazole].

The authors report a new Ketoconazole-induced hepatitis in which clinical, chemical and histological features show evidence of a cholestatic injury in a 62 yrs-old female recovering once therapy is stopped. In this case-report, delay of onset of the illness is very short for a 200 mg-a-day prescription and no feature leads towards an immune response. This, may be, means that Ketoconazole-induced hepatitis should be led by an idiosyncrasic mechanism. Even if fatal hepatitis are rare, prescriptors have to beware of this therapy.

Chemical and Drug Induced Liver Injury↗