PubMed Health⌕ Search

Biomedical subjects

J L Gallego

Publications and source records attributed to J L Gallego.

At least 19 recordsLinked to original sources
PubMed2001

Bioremediation of diesel-contaminated soils: evaluation of potential in situ techniques by study of bacterial degradation.

The development of a simple laboratory methodology allows the implementation of in situ bioremediation of polluted soils with diesel fuel. In this investigation microbiological and chemical analyses and a suitable bioreactor design, were very useful for suggesting the best ways to improve biodegradation extents in a diesel-enriched soil. Biostimulation with inorganic nitrogen and phosphorus produced the best results in a simple bioreactor, with biodegradation extents higher than 90% after 45 days. Also, the addition of activated sludge from a domestic wastewater plant increased the degradation rate to a great extent. In both cases, microbiological studies showed the presence of Acinetobacter sp. degrading most of the hydrocarbons. Simultaneously, a diesel fuel release (approximately 400,000 l) was studied. Samples taken in polluted soil and water revealed that bacteria from the genus Acinetobacter were predominant. In plate studies, Acinetobacter colonies produced a whitish substance with the characteristics of a biosurfactant. Remarkably, the presence of this product was evident at the field site, both in the riverbanks and in the physical recovery plant. The study of the similarities between laboratory results and the diesel spill site strongly suggested that natural conditions at the field site allowed the implementation of in situ bioremediation after physical removal of LNAPL (light nonaqueous-phase liquids).

Biodegradation, Environmental↗
PubMed1998

Post-kala-azar dermal leishmaniasis with mucosal involvement in a kidney transplant recipient: treatment with liposomal amphotericin B.

Post-kala-azar dermal leishmaniasis (PKDL) is a rare clinical variant of cutaneous leishmaniasis. It is very common in the Indian subcontinent and less frequent in East Africa, but exceptional in the American and European continents. We have observed a case of PKDL in a renal transplant recipient. No systemic symptoms were present. The patient was treated with liposomal amphotericin B. We emphasize the unusual aspects of this case: the appearance of PKDL in Europe, its relationship with immunosuppression, the severe mucosal involvement and the excellent response to liposomal amphotericin B, a newly described treatment for the disease.

Adult↗
PubMed1990

[Surgical treatment of postoperative mediastinitis in heart surgery using omentoplasty].

Among the 1,993 patients undergoing open-heart operations, our incidence rate of mediastinitis was 0.6%. Six patients have been treated with the pedicled omentum. Two of the 6 patients had a valvular disease and a coronary bypass the others. All patients had a good result with this procedure. After this experience, we think it is the best technique for management of this major complication.

Adult↗
PubMed1985

The bone scan in patients with aluminium-associated bone disease.

The bone scans of 32 patients on regular dialysis who received desferrioxamine therapy for fracturing osteomalacia secondary to aluminium intoxication are reviewed. All scans show the same pattern, with lack of tracer deposition in bone and deposition in soft tissues. Therapy with desferrioxamine controlled the aluminium intoxication in all cases, and in 21 patients the bone scan reverted to normal or showed a pattern typical of hyperparathyroidism.

Aluminum↗
PubMed1984

Serum concentration and peritoneal transfer of aluminum during treatment by continuous ambulatory peritoneal dialysis.

The evolution of the aluminum (A1) serum levels during a 2-year follow-up and the peritoneal transfer of A1 were studied in 22 patients treated by continuous ambulatory peritoneal dialysis (CAPD), using a dialysate with a very low A1 concentration (r = 0.25 - 0.30 mumoles/liter). Patients were divided in three groups. A transfer of A1 from the patient to the dialysate was observed in all patients. In group 1, patients exclusively treated by CAPD and who have never received aluminum-containing phosphate binders (ACPB), mean level (+/- SD) of serum A1 stabilized within a safe range (0.60 +/- 0.28 mumoles/liter). In group 2 the oral administration of ACPB in patients exclusively treated by CAPD induced a slow and progressive increase of A1 serum concentration despite the increase of the A1 excretion through the peritoneal route. In group 3, patients previously treated by hemodialysis and receiving ACPB, the high serum A1 levels observed before treatment by CAPD decreased rapidly on CAPD. A1 removal through the peritoneum was higher in group 3 than in group 2 despite serum A1 levels not statistically different in both groups. A1 removal through the peritoneum is mainly influenced by serum and dialysate A1 concentration. A1 body stores could play a role in the transfer of A1 through the peritoneum. Three cases of A1 poisoning due to the accidental use of a dialysate with a high A1 content are reported.

Adult↗
PubMed1983

Evolution of residual renal function in patients undergoing maintenance haemodialysis or continuous ambulatory peritoneal dialysis.

A study has been carried out to compare over an 18 month period the residual glomerular filtration rate (GFR) measured by the creatinine clearance in two matched groups of 25 patients with end-stage renal disease. One group was treated by continuous ambulatory peritoneal dialysis, the other one by maintenance haemodialysis. GFR was similar in both groups immediately before starting dialysis therapy, respectively 4.3 +/- 2.3 and 4.4 +/- 2.4 ml/min. From the beginning of the dialysis treatment to the eighteenth month there was a significant and progressive decrease of GFR in the group of patients treated by haemodialysis, while in the peritoneal dialysis group GFR and peritoneal clearances remained stable.

Adult↗
PubMed1980

[Plasmapheresis in the treatment of extracapillary glomerulonephritis (author's transl)].

Seven patients with widespread proliferation of the capilar epithelium producting glomerular crescents in more than 80 percent of the glomeruli have been studied. Three patients had a systemic lupus erythematosus, two had primitive extracapillary glomerulonephritis, one had panarteritis nodosa, and another a Schönlein-Henoch syndrome. All patients presented severe renal failure when plasmapheresis was begun. Hemodialysis was needed in four cases. The remained three patients showed creatinine clearance values of 8, 20, and 30 ml/min, respectively. Search for immune complexes was negative in all cases. Plasmapheresis were applied within 1 to 7 months of the onset of the disease in alternate-day sessions. Duration of treatment varied between 1 to 5 months. Moreover, prednisone, cyclophosphamide and azathioprine were given to all patients. Values of creatinine clearance rised to 71, 49 and 18 ml/min in the two patients with primitive extracapillary glomerulonephritis and in the patient with panarteritis nodosa, respectively. Renal function improvement was not achieved in the three patients with systemic lupus erythematosus and in the patient with Henoch's purpura.

Arteritis↗