PubMed HealthSearch

Biomedical subjects

J L Giunta

Publications and source records attributed to J L Giunta.

At least 19 recordsLinked to original sources

Peripheral, soft tissue odontomas. Two case reports.

Two cases of rare, peripheral, soft tissue odontomas, in different growth phases, are reported. Case one, discovered in an early, rapid growth phase, had no radiographic appearance, was presumed to be a periodontal abscess, and presented a diagnostic challenge. Case two was diagnosed radiographically in its mature phase. Both were treated successfully by excisional biopsy and did not recur. Comparisons are made to the classic intrabony odontomas.

Adult

Parakeratosis of the labial mucosa in zinc-deficient rats.

Epithelial parakeratosis has been observed in zinc-deficient animals of several species. In the rat, it has been reported on the epidermis, footpad, esophagus, soft palate, buccal mucosa, and dorsal tongue. This study reports that the lower lip also shows a striking hyperparakeratosis, as well as epithelial hyperplasia and an increase in mitoses. The appearance of these features was rapid with changes noted at Day 7 and persisting through Day 14 and Day 28. On Day 32, zinc was restored to the diet at control levels and by 42 days the zinc-deficient group showed dramatic increases in food intake, body weight, femur zinc and, in addition, mucosa of the lower lip resembled zinc-adequate controls. These differences are statistically significant. Morphometric comparison of spinous cells from zinc-deficients with those of the controls did not show significant differences.

Animals

Reflex vasoconstriction following dental injections.

Three case reports of transient facial blanching or vasoconstriction that followed administration of dental anesthetic are presented. A review of vasomotor cutaneous control is given, along with a proposal to explain this phenomenon.

Adrenergic Fibers

Bacterial plug versus pseudocyst of the tonsils.

This article presents several cases of two types of yellow lesions of the tonsils. The bacterial plug is a small, sometimes symptomatic lesion composed of mats of bacteria that fill a tonsillar crypt and is treated by dislodging the plug. The pseudocyst is a small, mostly asymptomatic smooth, epithelium-covered lesion that can regress spontaneously and need not be surgically removed for diagnosis. Both lesions are compared and contrasted to delineate diagnostic features and to suggest management. Terms are differentiated, and the relationship to the lymphoepithelial cyst is discussed.

Adult

Flushing of the face as a result of chewing food.

This case depicts a clinical situation in which the patient's face became flushed after chewing food for approximately 30 seconds. The distribution of the flushing accurately defines the distribution of the zygomaticofacial branch of the trigeminal nerve. A theory involving the parasympathetic supply to this area is presented to explain this clinical pattern.

Child

Facts about gonorrhea and dentistry.

This article reviews gonorrhea and discusses various misconceptions that have appeared in the dental literature and in verbal presentations about gonorrhea and dentistry. Facts are presented and some conclusions are offered for the dental profession.

Dentists

The reversibility of leukoplakia caused by smokeless tobacco.

This case describes an instance of reversibility of bilateral mucosal leukoplakic lesions caused by the long-term use of smokeless tobacco. The dentist should recognize the lesion, advise the patient to stop the tobacco usage, observe the reversibility of the lesion, and assist the patient in stopping the tobacco habit permanently.

Adult

Reticular mandibular gingival ridges.

This paper reports five cases of a heretofore unreported condition of the gingiva named reticular mandibular gingival ridges. Occurring in middle-aged males, macroscopically, they are bilateral ridges on the mandibular attached gingivae resembling rugae and having a reticular pattern that may be mistaken for lichen planus. Microscopically, they are formed of fibrous tissue with vessels that have a minimal perivascular infiltrate; the epithelium has extension of rete ridges. Of unknown etiology, the condition does not appear to change, is innocuous and does not require treatment.

Adult

Atypical central neurilemmoma of the mandible.

Neurilemmomas arising within the jawbones are rare. Most occur in the mandible as slowly growing enlargements that may or may not be painful; radiographically, they are large single or multiloculated radiolucencies mimicking other benign jaw lesions. The histology is characteristic, with Antoni A and B tissues and a well-defined capsule. This article reports an unencapsulated neurilemmoma of the mandible and reviews and summarizes the features of the central neurilemmomas in the literature.

Adult

Orofacial involvement secondary to trapezius muscle trauma.

The case reported in this article demonstrates an unusual referral mechanism for signs and symptoms of the face and the oral cavity emanating from a traumatized trapezius muscle. A theory for this referral, based on central connections of nerves V, VII, IX, X, and XI, is proposed.

Adult

The median mandibular cyst and its endodontic significance.

The median mandibular cyst is a very rare cyst of debatable origin that occurs in the midline of the mandible. A review of the literature and an additional case are presented, with emphasis on diagnosis, treatment planning and the need for endodontic therapy in the area of the lesion.

Child

Studies on the vascular drainage system of the hamster buccal pouch.

Because some investigators feel that the hamster buccal pouch is an immune privileged site with no lymphatic drainage, this study was done to demonstrate and further elucidate a drainage system from the pouch to the cervical nodes. Eight hamsters were injected with india ink, submucosally in the right pouch. Dissections at one or 2 days revealed ink in macrophages in the right submandibular nodes at 2 days. Histologically, the ink was noted within macrophages which aggregated around blood vessels. No lymph vessels were noted in the pouch. Six hamsters were injected with fluorochrome-labelled latex microspheres. At 2 and at 4 days the microspheres were noted in both the pouches and the ipsilateral submandibular nodes. The results indicate there is a delayed lymphatic drainage from cheek pouches to the submandibular nodes mediated by macrophages.

Animals

The effect of dinitrochlorobenzene (DNCB) on dimethylbenzathracene (DMBA) carcinogenesis on hamster buccal pouch.

DNCB is an antigen that stimulates the cell-mediated response in a sensitized host. The purpose of this study was to define the effect DNCB would have on a standard model system for oral carcinogenesis, theorizing that tumorgenesis would be delayed or inhibited. Fifty-six Syrian hamsters were divided into four groups. In group A (DNCB/DMBA), the right buccal pouch of twenty animals was treated with 2% DNCB in orabase, twice a week, and 0.5% DMBA, three times a week, for 10 weeks. In group B, twenty animals received DMBA only. In group C, six animals received DMBA in Orabase. In group D, ten animals received DNCB in Orabase only. The animals were killed at 6, 12, 16, and 20 weeks. The results indicate that there were no differences in the latent period or in the histologic characteristics of the epidermoid carcinomas that developed. However, there was sensitization of the buccal pouch in pouches painted with DNCB, in that gross and histologic evidence of a delayed sensitivity reaction was demonstrated.

9,10-Dimethyl-1,2-benzanthracene