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Biomedical subjects

J L Halbrecht

Publications and source records attributed to J L Halbrecht.

7 recordsLinked to original sources

Internal impingement of the shoulder: comparison of findings between the throwing and nonthrowing shoulders of college baseball players.

The authors evaluated and compared the findings of gadolinium-enhanced magnetic resonance imaging (MRI) studies of throwing and nonthrowing shoulders in college baseball athletes and contrasted these findings with the clinical examination results. Ten throwing college baseball athletes were prospectively clinically examined for instability, range of motion, impingement signs, and relocation testing, then evaluated with bilateral gadolinium enhanced MRI using the nonthrowing shoulder as a control. All MRIs were performed on a 1.5-Tesla magnet and included routine adduction images and images obtained in abduction and external rotation (ABER). Studies were interpreted by a musculoskeletal radiologist and an orthopaedic surgeon specializing in shoulder surgery. In all shoulders, ABER imaging showed physical contact between the undersurface of the rotator cuff and the posterior superior glenoid. No imaging or physical examination abnormalities were identified in the nonthrowing shoulders. Three of 10 throwing shoulders had superior labral tears and adjacent paralabral cysts extending toward or into the spinoglenoid notch. Four of 10 throwing shoulders had abnormal signal change in the rotator cuff tendons. No correlation was identified between positive MRI findings and instability on physical examination. Physical contact between the rotator cuff undersurface and the subjacent labrum can be seen normally in the ABER position. Abnormalities of the rotator cuff and superior labrum are seen in asymptomatic throwing shoulders but not nonthrowing shoulders. MRI abnormalities consistent with internal impingement can be seen in asymptomatic patients. Treatment of these abnormalities in young throwing athletes should be approached with caution.

Adult↗

Office arthroscopy of the shoulder. A diagnostic alternative.

Office arthroscopy of the shoulder is a technically demanding procedure and is significantly more challenging than office arthroscopy of the knee. With the proper equipment and in the hands of an experienced shoulder arthroscopist, the procedure offers many advantages. Patients unanimously prefer office arthroscopy to MR imaging because of the ability to view their pathology personally in a medium more palatable and understandable than MR imaging. Office arthroscopy appears to be a safe, accurate, and cost-effective alternative to MR imaging for the diagnosis of shoulder pathology in select patients.

Arthroscopes↗

Office arthroscopy: a diagnostic alternative.

Twenty patients with enigmatic knee symptoms were selected for evaluation by both magnetic resonance imaging (MRI) and office arthroscopy. Office arthroscopy was performed in a standard examination room using a miniature (1.7 mm) fiberoptic arthroscope under local anesthesia. All MRI scans were performed on a state-of-the-art 1.5-T magnet unit, and included specialized cartilage sequences in 7 patients. In 14 patients, 26 areas showed articular cartilage changes by arthroscopy (grade 2-3). Only nine of these areas were detected by MRI (sensitivity 34.6%). There were five false-positive and four false-negative readings of meniscal tears by MRI as compared with office arthroscopy. These results improved when postoperative menisci were excluded. Only one of three anterior cruciate ligament (ACL) disruptions identified by MRI could be verified by arthroscopy. The one posterior cruciate ligament (PCL) disruption was confirmed by both techniques. MRI was superior to arthroscopy in identifying bone contusions, subchondral sclerosis, and medial cruciate ligament (MCL) sprains. Office arthroscopy is an accurate and cost-efficient alternative to MRI in diagnostic evaluation of knee pathology in patients with enigmatic symptomatology.

Adolescent↗

Recurrent dislocation of the proximal tibiofibular joint.

Recurrent dislocation of the proximal tibiofibular joint is a rare injury. This report presents a case of bilateral recurrent dislocations of the proximal tibiofibular joint in a jet skier that responded to physical therapy and activity modification. A review of the literature is provided, with attention to the mechanism of injury and other treatment options--including arthrodesis and resection of the proximal fibula. This diagnosis should be considered in jet skiers with lateral-sided knee pain.

Adult↗

Unusual fragment displacement in a distal radius fracture.

A 25-year-old man sustained a closed comminuted intra-articular fracture of the distal radius. Tomography showed 180 degree rotation of a palmar medial articular fragment. This rare injury is mentioned only once in the literature. When recognized, open reduction and internal fixation are necessary.

Adult↗

Effect of cimetidine on delta-aminolevulinic acid synthase and microsomal heme oxygenase in rat liver.

Cimetidine is a well known inhibitor of the heme-containing enzyme cytochrome P-450. We have found that it also inhibits delta-aminolevulinic acid synthase (ALA-S) and microsomal heme oxygenase, the rate-limiting enzymes for heme synthesis and heme degradation respectively. Cytochrome P-450 content was decreased but microsomal heme concentration remained unaltered for a period of 30 min after in vivo cimetidine administration to rats. In vitro incubation of cimetidine with each of the above enzymes revealed no direct effect of cimetidine on ALA-S but about 50% inhibition of heme oxygenase and 20% reduction in cytochrome P-450 content. This suggests that a metabolite of cimetidine inhibits ALA-S activity in vivo, while the drug itself or a metabolite inhibits heme oxygenase both in vivo and in vitro. A rise in ALA-S activity seen after its early inhibition and its return to approximate control values after 60 min suggest a reversible inhibition of ALA-S by a metabolite of cimetidine and may correspond to its clearance from the animal. An elevation in microsomal heme content paralleled the rise in ALA-S activity while microsomal heme oxygenase activity returned to only 65% of control value 60 min after cimetidine treatment. Cytochrome P-450 content did not change after its initial decrease, suggesting that irreversible alteration had occurred.

5-Aminolevulinate Synthetase↗

Arthroscopic patella realignment: An all-inside technique.

PURPOSE: Many methods of realigning the patella have been described. Most techniques for proximal realignment involve an open medial reefing or advancement of the vastus medialis obliquus. Arthroscopically assisted methods have been described, but these all involve the need for a medial incision to tie sutures. This article describes an entirely arthroscopic technique for proximal realignment that eliminates the need for an incision, and reports the 2-year follow-up results using this technique. TYPE OF STUDY: Retrospective review. METHODS: Over a 5-year period, 26 patients (29 knees) with patellar instability were treated with an outpatient arthroscopic all-inside medial reefing and lateral release. Arthroscopic reefing was performed by percutaneous passage of suture followed by arthroscopic retrieval and knot tying inside the joint. Before knot tying, a healing response was initiated along the medial retinaculum by either gentle shaving with a whisker blade or by radiofrequency thermal response. Rehabilitation consisted of 1 week of immobilization followed by an accelerated program of range of motion exercises and vastus medialis obliquus strengthening. RESULTS: At follow-up, 93% of patients reported significant subjective improvement. The average Lysholm score improved from 41.5 to 79.3 (P <.05). Preoperative and postoperative radiographs were measured for congruence angle, lateral patellofemoral angle, and lateral patella displacement, and all showed significant improvement postoperatively (P <.05). There were no complications and no redislocations. Patients reported a significant improvement in pain, swelling, stair climbing, crepitus, and ability to return to sports (P <.05). CONCLUSIONS: Arthroscopic patella realignment is a viable technique that offers results comparable or superior to published results for open or arthroscopically assisted realignment.

Adolescent↗