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Biomedical subjects

J L Koltai

Publications and source records attributed to J L Koltai.

8 recordsLinked to original sources

Significance of arthroscopy in children with knee joint injuries.

Clinical and arthroscopic findings after knee joint injury were evaluated in 35 children aged 4-15 years. Arthroscopy revealed a rupture of the anterior cruciate ligament in 9 patients; two lesions were only partial. Eight children suffered from patellar dislocation. Eleven patients showed minimal synovial and cartilaginous lesions as the only cause of hemarthrosis, hydrarthrosis and clinical symptoms. Three had chondral lesions due to a dysplastic patella. The clinical diagnosis was confirmed in only 12 of 35 cases. Arthroscopic therapy was performed in 15 and open surgical intervention in 16 patients. Our results show that hemarthrosis and persisting symptoms after a knee trauma in children indicate a severe knee injury. The diagnostic procedure and treatment should be as ambitious as in adults.

Adolescent

Intraperitoneal application of fibrinogen gluing in the rat for adhesions prophylaxis.

The suitability of fibrinogen gluing for prophylaxis of intraperitoneal adhesions was investigated experimentally. Small bowel slings, traumatized previously, were covered by a layer of fibrinogen 2-3 mm thick to see whether formation of adhesions could be prevented. In the experiments 50 rats of both sexes were observed over 21 days. Following mechanical traumatization of the terminal ileum the visceral peritoneum was coated with fibrinogen, whereas animals of the control group did not receive fibrinogen coating. Macroscopic and microscopic findings after 1, 3, 7, 14 and 21 days yielded the following results: 1. Fibrinogen dissolution and resorption occurred for 3-14 days following operation. 2. On autopsy, all animals of the control group showed massive, extended adhesions; two of the controls died on the 6th postoperative day from peritonitis. 3. None of the treated animals exhibited extended adhesions. 4. Histological examinations revealed regeneration of the injured serosa and healing of the bowel wall below the fibrinogen coating. 5. Fibrinogen applied to intact peritoneal serosa (without injury) is entirely resorbed without formation of adhesions.

Animals

[Improving continence by reoperation].

Between 1969 and 1988, 191 children underwent operations for anorectal anomalies in the Pediatric Surgical Department of Mainz University Hospital. Ninety-six had deep and 84 had intermediate or high malformations; the type was unknown in 11. Of these patients 53 had impaired continence and 8 still have a protective colostoma. 37 of the remaining 45 children had check-ups and reoperations (5 were deep types). After reoperation there was full continence in 14 patients, partial continence in 11, persisting incontinence in 11 and one case could not be assessed. Our results recommend reoperation using modern surgical methods of patients with continence.

Anus, Imperforate

[Improving continence by biofeedback conditioning].

In the last 10 years biofeedback training (BFT) has been used in 72 patients with anal continence disturbances following rectoanal agenesis, constipation, MMC, etc. Using the BF-method we treated 35 children with incontinence following rectoanal agenesis (5 infralevator, 30 supralevator). Visual analog feedback was used in the first 10 cases. Since 1982 simultaneous audiovisual analog signals have been preferred. The detailed analysis and personal followup over 6.5 years of these patients suggests that BFT improves the threshold of rectal sensation, voluntary contraction and thereby benefits anal continence.

Adolescent

[Surgical therapy of primary hyperparathyroidism in newborn infants].

This is a report on a neonatal primary hyperparathyroidism (NPHPT) treated by total parathyroidectomy and autotransplantation of parathyroid tissue into the forearm musculature. Histologically, the glands were composed of a "chief cell hyperplasia" of the parathyroid tissue. Clinical manifestation in neonates and differential diagnosis of HPT are discussed. Indication for operation and surgical procedure are described.

Humans

[Surgery of the juvenile adrenal glands. Surgical protocol, intra- and perioperative monitoring].

Surgical and non-surgical conditions of the adrenal cortex and medulla are presented. Besides general principles of operative treatment (e.g. surgical approach, safe operative technique, bilateral exploration) specific aspects associated with this procedure in childhood are discussed. The perioperative management and pharmacotherapeutical preparation (e.g. hormonal substitution) are emphasized.

Adrenal Gland Diseases

[Mesenteric cysts in childhood].

5 children with mesenteric cysts, 3 boys and 2 girls, aged 2 to 10 years, were admitted with acute abdominal pain. In adults the most common symptom is chronic abdominal pain whereas in children the onset of symptoms is acute due to intestinal obstruction. Sonography, performed in two patients, is the diagnostic method of choice. Excision of the cyst required resection of the small intestine in 2 patients, while simple enucleation was possible in 3. All 5 patients survived, and there have been neither complications nor recurrences. Early recognition and appropriate resection of these occasionally life-threatening malformations are associated with a good prognosis.

Abdomen, Acute

[Methodologic studies of manometry of the rectum].

For the purpose of an experimental study in which the three different types of pressure catheters most commonly used in anorectal manometry were compared, a Starling-resistance could be established. Under equal conditions the pressures could be changed in this resistance and the data obtained by using a membrane-catheter, an open-tip and an open-side-catheter were compared among one another and to the known ideal straight line. The open tip catheter measures the opening pressure and the recorded pressure does not necessarily reflect the pressure at the site of the tip hole. Because of its elastic and plastic characteristics, the membrane-catheter yielded the best results with prestretch of the membrane and with calibration before and after each study.

Anal Canal