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Biomedical subjects

J L Kupper

Publications and source records attributed to J L Kupper.

17 recordsLinked to original sources
PubMed1979

Selection and pairing of 'normal' rhesus monkeys (Macaca mulatta) for research: procedures, techniques, and observations.

A selection process has been developed by the authors to insure investigators that animal subjects used in their experiments will accurately reflect biological changes associated with the project design. The procedure involved the following: complete physical examination; complete hemogram, serum electrolytes, serum biochemistry, body weight; and anthropometric determinations; aging by dentition; electrocardiography; total-body radiography; fecal culture; fecal ova, and parasite examinations; and examination of other conditions. Arithmetic means and standard deviations were calculated and used to eliminate monkeys whose values varied from the mean by more than two standard deviations.

Animals↗
PubMed1977

Accidental methyl methacrylate inhalation toxicity in a rhesus monkey (Macaca mulatta).

A rhesus monkey (Macaca mulatta), accidentally exposed to vapors of methyl methacrylate for 22 hours was found in a comatose condition. Attempts to revive the animal were unsuccessful. Necropsy revealed a diffusely mottled liver, pulmonary edema, and atelectasis. The thoracic cavities each contained 30 ml of clear yellow fluid. Histopathologic review of the tissues showed central lobular liver necrosis, pulmonary edema, pulmonary emphysema, and atelectasis. Analysis of a blood sample obtained from the monkey 1.5 hours prior to death showed a normal hemogram, but elevated values for serum glutamic oxaloacetic transaminase, serum glutamic pyruvic transaminase, lactate dehydrogenase, phosphohexose isomerase, blood urea nitrogen, and serum sodium. The pathologic findings, laboratory results, and clinical history suggested a diagnosis of methyl methacrylate poisoning.

Animals↗
PubMed1976

Obstructive gastric foreign body in a rhesus monkey (Macaca mulatta).

Weight loss and depression were the principal signs in a case of obstructive gastric foreign body resulting from the ingestion of pine wood fragments by a rhesus monkey. This was the second case of its kind to occur in a short period. Replacement of the monkeys' pine wood resting platforms with platforms made of oak eliminated the problem.

Anemia, Hypochromic↗