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J L Ma

Publications and source records attributed to J L Ma.

26 records · Page 2Linked to original sources

[Churg-Strauss vasculitis].

The author reported a clinical study of 8 cases of Churg-Strauss vasculitis which is a rare disease of unknown cause. The clinical features include allergic rhinitis (69%), sinusitis (88%), asthma (98%-100%), mononeuropathy (66%-98%), pulmonary infiltration and peripheral blood eosinophilia. The histopathologic manifestations are characterized by eosinophilic infiltration, granulomatous lesion and necrotising vasculitis. The lesions mentioned above may not appear simultaneously, but they may exist in different combinations. Therefore, not all the manifestations may be seen in a single biopsy specimen. According to the diagnostic criteria recommended by American College of Rheumatology Subcommittee on Classification of Vasculitis in 1990, 6 cases of this series can be diagnosed. The remaining 2 cases were confirmed by pathologic examination. This kind of vasculitis responds to steroid treatment with satisfactory results.

Adult↗

[Studies on constituents of ganoderma capense IV. The chemical structures of ganoine, ganodine and ganoderpurine].

Two novel pyrrole alkaloids--ganoine and ganodine and a novel purine alkaloid ganoderpurine have been isolated from the mycelium of Ganoderma capense (Lloyd)Teng (Polyporaceae) obtained by submerged fermentation. On the basis of spectroscopic data their structures were elucidated, ganoine is N-isopentyl-5-hydroxymethyl-pyrryl alldehyde. Ganodine is N-phenylethyl-5-hydroxymethyl-pyrryl aldehyde and ganoderpurine is N9-(alpha, alpha dimethyl-gamma-oxobutyl) adenine.

Adenine↗

The efficacy of triclabendazole (Fasinex) against immature and adult Fasciola hepatica in experimentally infected cattle.

Eighteen Chinese cattle were experimentally infected with metacercariae of Fasciola hepatica and randomly assigned to 6 groups. Five groups of cattle were treated with a single oral dose of triclabendazole at a dose rate of 12 mg kg-1. At necropsy, the reduction in fluke burden compared with the untreated group was 85, 99.6, 99.8, 100 and 100% for cattle treated 2, 6, 8, 12 and 16 weeks after infection, respectively. Data are also presented on body weight changes during the experimental period and on serum gamma-GT activity in cattle from selected groups. Triclabendazole is considered to be safer and more efficacious than currently available fasciolicides in China.

Animals↗