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Biomedical subjects

J L Marcos Rodríguez

Publications and source records attributed to J L Marcos Rodríguez.

7 recordsLinked to original sources
PubMed1994

[Nonelective colorectal surgery. Does age determine the results?].

OBJECTIVE: To evaluate the influence of age on the morbi-mortality after non-elective colorectal surgery. DESIGN: Retrospective analysis. SUBJECTS: 150 consecutive patients who underwent non-elective colorectal surgery between 1986 and 1992 [65 patients aged under 70 years (Group I)] and 85 patients aged 70 years or over (Group II)]. RESULTS: Using multiple regression analysis we have found: 1) Mortality is determined by the presence of associated risk factors (p < 0.001 tv = 4.11), the presence of peritonitis (p < 0.05 tv = 2.08) and by the admission-operation interval (p < 0.05 tv = 2.10). 2) Overall morbidity increases with age (p < 0.01, tv = 3.22) and the benign nature of the colorectal disease (p < 0.05, tv = 2.00). CONCLUSION: Age does not influence mortality in non-elective colorectal surgery even though it is a determinant risk factor in morbidity increase.

Age Factors↗
PubMed1993

[Idiopathic ulcer of the small intestine].

Two cases of multiple idiopathic ulcers of the small intestine are reported, which were found in two aged patients with a significant history of vascular pathology. Despite this, the pathological examination of the surgical specimens could not demonstrate a vascular origin of such lesions.

Aged↗
PubMed1993

[Appendicular invagination].

Two cases of intussusception of the appendix are reported. The first case stands out for its rarity, corresponding exclusively to intussusception of appendicular mucosa. The second case was due to cystoadenoma of the appendix. Both cases were treated by right hemicolectomy due to the difficulty of diagnosing the condition.

Aged↗
PubMed1992

Post-vagotomy variations of gastric mucosal mast cells in the rat.

The effects of the vagus and its action on the mucosal mast cells (MMC) of the secretory portion of the rat stomach are analyzed by observing the consequences caused by subdiaphragmatic truncal vagotomy on the MMC in terms of cell count and degranulation over a period of four months. Observations showed a gradual decrease in the number of mast cells/mm2, an increase in the percentage of MMC in a state of degranulation, but the same number of degranulated cells/mm2. This suggests that the vagus controls both numerically and functionally the MMC population in the secretory portion of the rat stomach.

Animals↗
PubMed1992

[Digestive hemorrhage caused by vascular malformation (Rendu-Osler-Weber). A diagnostic and therapeutic challenge].

We present a case of gastrointestinal bleeding due to vascular malformation (Osler-Weber-Rendu disease), without cutaneous manifestations but with mucous manifestations and familiar and personal history of epistaxis. Until diagnosis, the patient underwent multiple radiologic and endoscopic tests and two surgical procedures. We would underline the diagnostic and therapeutic difficulty of recurrent gastrointestinal bleeding secondary to vascular malformation.

Gastrointestinal Hemorrhage↗
PubMed1991

[The short-, median- and long-term changes of mastocyte degranulation in the gastric submucosa of rats following truncal vagotomy].

We study the effect of the truncal vagotomy on the degranulation activity of mast cell population in the submucosa of the rumen and fundus of the stomach of the rat after 7, 30, 60, 90 and 120 days of the surgical procedure. Also we analyze if the observed variations are connected with the existence or not of secretory activity in the studied area. The degranulation activity decreases in 7 days in the fundic secretory area with statistic significance, but not in the rumen. A significant increase of the degranulation is seen in both areas, after 90 days. We conclude that the effects of the vagotomy on mast cell degranulation in the submucosa of the stomach of rats depend on the presence or not of secretory activity in the studied area and the length of time after the surgical procedure.

Animals↗