Biomedical subjects
Publications and source records attributed to J L Menetrat.
Paralytic poliomyelitis were observed in two healthy children who both had previously received four doses of standard inactivated poliovaccine (IPV). These children, whose immune defenses were normal, failed to respond to IPV. This absence of antibody response might be related to an insufficient antigenicity of inactivated vaccines, justifying the extensive use of the more potent IPV, now produced on continuous cell lines.
Explore the source record for details and available documents.
With live measles freeze-dried vaccine, accelerated storage test provides more information than does a titration of residual moisture. From our results, it appears that there is a good correlation between storage at 37 degrees and the tests usually required by the manufacturer, i. e. storage for 1 year at refrigerator temperature. The accelerated test in neither tedious nor expensive and is recommended for routine use.