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Biomedical subjects

J L O'Quinn

Publications and source records attributed to J L O'Quinn.

10 recordsLinked to original sources
PubMed1995

Worksite wellness programs and lifestyle behaviors.

Do employees who participate in worksite wellness programs differ from those who do not? What health-related lifestyle behaviors are practiced most frequently by which employees? A descriptive, correlational, comparative design was used to investigate these questions. Four hundred employees at a large public university were selected through stratified random sampling to complete a demographic sheet and the Health Promoting Lifestyle Profile (HPLP). Study findings revealed that men used self-actualization and exercise behaviors more frequently than women. Women practiced more health responsibility behaviors than men. Employees who were members of the wellness program more frequently practiced health responsibility and exercise behaviors than nonmembers. Overall, wellness program members used a greater number of the total health-related behaviors than other employees. Membership in the wellness program and the number of times per week a person exercised explained 21% of the variance in the HPLP scores.

Adult↗
PubMed1994

Histogenesis of vascular tumors in the Proteus syndrome.

Proteus syndrome (PS) is a congenital disorder manifesting with severe deformities, the salient features being gigantism and vascular tumors. The disorder is poorly understood, and there has been much discrepancy in the terminology regarding the vascular tumors in PS. The purpose of this study was to elucidate the histogenesis of these tumors by correlating microscopic observations with immunohistologic information. The value of immunoperoxidase studies in the pathologic evaluation of PS was also assessed. Fourteen formalin-fixed, paraffin-embedded tissue specimens obtained from vascular tumors of six children with PS were stained with Ulex europaeus agglutinin I (UEA-I) lectin and the following immunohistochemical reagents: anti-factor VIII-related antigen (FVIII-RAg) and anti-CD34. The tumors showed varied proportions of vascular, lipomatous, and fibrous tissue components consistent with vascular hamartomas. The predominant vascular channels of the tumors were morphologically consistent with lymphatic vessels. Immunostaining of the endothelium of these vessels was most consistently positive with UEA-I lectin. Although a color reaction product was present in small vessels and some larger blood vessels, anti-CD34 immunostaining spared the lumens of lymphatic channels. In addition, a striking population of dendritic spindle cells was noted with the anti-CD34 but was unnoticed with the other reagents. We concluded that the vascular tumors of PS are primarily lymphatic hamartomas. The spindle cells noted with anti-CD34 immunostaining may relate to angiogenesis and need further delineation.

Adult↗
PubMed1991

Granular cell tumor of the biliary tree. A report of two cases and a review of the literature.

Granular cell tumors are relatively uncommon soft tissue tumors usually presenting in the skin and subcutaneous tissues or tongue, although many sites have been described. Two cases arising in the extrahepatic biliary tree are described, and the previously reported cases of this rare presentation are reviewed. These tumors may mimic sclerosing cholangitis and cholangiocarcinoma clinically, and occasionally histologically, in this relatively young group of patients. The histogenesis appears to be related to Schwann cells as in granular cell tumors of other sites, evidenced by histologic, immunohistochemical, and electron microscopic findings. Granular cell tumors, albeit rare, should be considered in the differential diagnosis of biliary tract disease in young patients, particularly black women, and are curable by surgical excision.

Adult↗