Biomedical subjects
Publications and source records attributed to J L Outeda.
Fifteen patients suffering from inflamatory diseases of the colon (14 nonspecific ulcerous recto colitis and 1 Crohn disease) were complicated with involvement of large joints and spine (ankylosing spondelytis). The clinic, radiology, pathology, seriology and evolution of ankylosing spondylitis were considered in relation-ship with inflamatory disease of colon.
The esophageal response studied in the systemic illness has been developed clearly in the body of the esophagus as well as in the lower esophageal sphincter, showing important alterations in the peristalsis and a significant fall of lower esophageal sphincter pressure, proving conditions such as those in which gastro-esophageal reflux is produced. The authors studied the esophageal motility in 10 patients with progressive systemic sclerosis by electromanometry by means of an open-tipped catheters system. They found that the pressure of the inferior esophageal sphincter was altered in the 100 per cent of the cases; in 50% of the patients there was a lack of peristaltic waves and in the remaining 50% the middle pressure was less than in normal subjects. It was observed dysquinethic waves in 40% of the cases. The intensity of the epidermic compromise is no related with alterations in the esophageal functioning.
A case of much less frequent association of the pyoderma gangrenosum and granulomatous disease of the colon (Crohn's disease of the colon) is presented. A literature review is made about the association of the same with other gastrointestinal affections. It is brought up to date the possible atiopathogenical mechanisms and therapeutical effects.
The authors present 17 patients with progressive systemic sclerosis studied at the Hospital Nacional de Gastroenterología "Dr. Carlos Bonorino Udaondo" (Buenos Aires), in the period between 1976-1980. Clinical, radiological, endoscopical and manometrical studies of the digestive tract was performed, showing frequent compromise in this collagen disease.