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Biomedical subjects

J L Paradise

Publications and source records attributed to J L Paradise.

At least 91 records · Page 5Linked to original sources
PubMed1976

Clinical trials of tonsillectomy and adenoidectomy: limitations of existing studies and a current effort to evaluate efficacy.

Indications for tonsillectomy and adenoidectomy (T&A) are both uncertain and controversial. Only five prospective clinical trials of T&A have been reported. These studies provided important data, but failed to test the efficacy of the procedures in children most affected by tonsil- and adenoid-related conditions. A study currently under way focuses on just such children and also explores related immunologic issues.

Adenoidectomy↗
PubMed1976

Tympanometric detection of middle ear effusion in infants and young children.

Tympanometry, a test of middle ear status new to clinical pediatrics, was carried out on 280 subjects, 10 days through 5 years of age. The tympanograms obtained were compared with otoscopic findings and, in 107 of the subjects, with findings at myringotomy. Seven distinct tympanometric curve types were identified and defined, based on their degree of correlation with the presence or absence of middle ear effusion. In subjects 7 months of age and older, curves suggesting normal (high) tympanic membrane compliance in combination with atmospheric or near-atmospheric middle ear air pressure were rarely associated with effusion. Conversely, curves suggesting low tympanic membrane compliance were highly correlated with the presence of effusion. Curves suggesting intermediate compliance or reduced middle ear air pressure were also correlated with effusion, but the degree of correlation was dependent on the shape of the curve. In infants less than 7 months of age, many of the ears with effusion had "normal" tympanograms, presumably because external auditory canal walls in such infants tend to be highly distensible. Tympanometry is a simple, rapid, atraumatic, valid, and objective test, easily administered by paraprofessional personnel. Its use can result in improved detection of middle ear effusion and other middle ear abnormalities, and also appears to promote improvement in diagnostic acumen.

Child, Preschool↗