PubMed HealthSearch

Biomedical subjects

J L Patrick

Publications and source records attributed to J L Patrick.

2 recordsLinked to original sources

Reducing motion artifacts in two-dimensional Fourier transform imaging.

The effects of motion in two-dimensional Fourier transform imaging (2DFT) are considered. Specific calculations describing the case of periodic motion are presented. The results predict the commonly seen artifact of image replication, sometimes referred to as ghosting. Expressions for both position and amplitude of these ghosts are derived. Simulated examples illustrate the image degradation for pulsatile flow and in plane motion. Several methods of reducing motion artifacts are then suggested. These include: randomization of views, averaging views, matching repeat times to the respiratory period, hybrid imaging, ROPE and COPE. The latter two methods reorder the data acquisition to destroy the coherence of the motion. They do not increase the data acquisition time and promise to be part of the standard approach to remove motion artifacts. The final step in actually recovering ideal resolution can be accomplished by using a model of the motion and a generalized transform inversion technique.

Fourier Analysis

Visualization of brain iron by mid-field MR.

Brain iron was visualized on a mid-field (0.5 T) scanner using a spin-echo pulse sequence. Methemoglobin was hyperintense on T1- and T2-weighted images. Deoxyhemoglobin, hemosiderin, and ferritin were seen as decreased intensity on T2-weighted images. The spin-echo pulse sequences were improved for identification of deoxyhemoglobin, hemosiderin, and ferritin by prolonging the TR to 3000 msec and the TE to 80-120 msec. Phase-encoding artifacts at the level of the sylvian fissures caused increased noise, obscuring the brain iron in the lentiform nuclei with the TE of 120 msec. This artifact was substantially reduced or eliminated by lowering the TE to 80 msec, changing the phase-encoding gradient to the Y axis, or using additional pulsing in the slice and read gradients. Use of either the improved spin-echo or gradient-echo pulse sequences on a mid-field MR scanner provides improved evaluation of brain iron.

Brain Chemistry