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Biomedical subjects

J L Pearce

Publications and source records attributed to J L Pearce.

33 records · Page 2Linked to original sources

The use of the microagglutination technique to determine the antibody status of healthy New Zealanders to Brucella abortus.

Sera from healthy blood donors from different parts of New Zealand, collected between 1977 and 1980, were analysed by the microagglutination technique for antibodies against Brucella abortus. Populations from both urban and rural areas were studied. The technique was shown to be capable of handling the 3351 sera studied and thus to be a useful screening test to assess the immune status of large populations. The results demonstrated some of the effects on the human population of the successful bovine brucellosis eradication programme.

Adult

Prospective study of convulsions in childhood.

One hundred and five children admitted to hospital with convulsions were studied prospectively. A convulsion was designated febrile if an axillary temperature of 38 degrees C or more occurred after the fit. Twenty-two children had an initial non-febrile convulsion and five of them (22.7 percent) have developed recurrent nonfebrile seizures. In the febrile group of 83 only two children (2.4 percent) have so far had non-febrile convulsions. Both their initial convulsions were uncomplicated. There was no difference between the groups of convulsion or EEG result. Investigations in hospital, including lumbar puncture, rarely revealed a diagnosis not clinically suspected. In previously healthy children with convulsions that are not prolonged, pyrexia is the only factor of prognostic significance by 12 months follow up.

Female

Breast milk and breast feeding in very low birthweight infants.

The feeding of 17 babies weighing less than 1500 g was examined retrospectively. 12 babies started breast feeding at a mean weight of 1324 g and 10 of them were fully breast fed by a mean weight of 1600 g. Their weight gains were comparable with bottle-fed babies receiving expressed breast milk. Practical aspects of breast feeding were considered to be: a knowledgeable maternal and nursing attitude, close mother and baby contact, early expression of breast milk, and early suckling. The increased incidence of breast feeding by mothers of both low birthweight and term babies ensures regular supplies of fresh breast milk. Therefore, sterilisation or storage of breast milk there is unnecessary.

Breast Feeding

Modern simple extracapsular surgery.

A series of 444 aphakic eyes is reviewed in which extracapsular extraction was performed by modern simple instrumentation followed by the insertion of a posterior chamber lens. The visual results of 93.5 per cent seeing 6/12 (20/40) or better in an age group of 70 years plus is satisfactory. The hospitalization is short and visual recovery rapid. Complications have been few and it has been shown that peripheral iridectomy is not required in most cases as they are not subject to pupil-block glaucoma. The main problem with extracapsular extraction is the incidence of needlings of 9 per cent rising to 16 per cent with longer follow-up. Despite this it is felt that the advantages of extracapsular extraction, with rapid visual rehabilitation and a lower incidence of cystoid macular oedema and retinal detachment, outweigh the disadvantages.

Aged

Sixteen months' experience with 140 posterior chamber intraocular lens implants.

Three main designs of posterior chamber lenses in 140 cases have been reviewed. The visual results are satisfactory; patient satisfaction is good; and postoperative complications are limited to anterior dislocation of the feet of the lens and the necessity to wash out cortical remnants from behind the prosthesis in a small percentage of cases. The posterior chamber prosthesis is free from some of the complications of other intraocular lenses and probably provides the most 'normal' looking eye of any pseudophakoi.

Adolescent

Phenobarbital in the acute management of febrile convulsions.

Blood levels of phenobarbital were determined after a single oral or intramuscular (IM) dose in children in the hospital after febrile convulsions. At a dose of 15 mg/kg, both the oral and IM routes gave therapeutic blood levels within 90 minutes. Absorption from the IM route before 90 minutes was inconsistent and would be unlikely to arrest an established convulsion within a critical time period. For use as a drug to prevent convulsions, oral phenobarbital at 15 mg/kg deserves further study.

Child, Preschool

Experience with 194 posterior chamber lenses in 20 months.

The author describes his experience with 194 posterior chamber lenses, mainly of the Pearce tripod variety. The surgical technique and complications peculiar to this type of prosthesis are considered. It was found that 75 per cent of eyes saw 6/9 or better and that the visual results compared favourably with figures given by other workers using different types of implants. The tripod posterior chamber lens is free of some of the problems associated with other intraocular lenses, especially pupil block glaucoma, hyphaemata, and the contact with plastics of the corneal endothelium. It is felt that the posterior chamber deserves further consideration as the correct place for an intraocular lens, because it provides a more "normal" eye than any other prosthesis.

Adult

Surgical and postoperative problems with Binkhorst 2- and 4-loop lenses.

The operative and postoperative complications are described in a series of 537 eyes with lens implants, with suggestions for prophylaxis and treatment. The level of complications is low, and the authors believe that the visual results in terms of patient satisfaction make lens implantation a worthwhile procedure.

Adolescent

Long-term results of the Choyce anterior chamber lens implants Marks V, VII, and VIII.

68 eyes in which Choyce Mark VIII anterior chamber lenses had been implanted were examined, all surgery having been performed by Mr. Choyce. The average time since implantation was 5-5 years aand in 85 per cent. of eyes the corrected visual acuity was 6/12 or better. Bullous keratopathy, corneal epithelial oedema, and peripheral anterior synechiae giving rise to glaucoma were the most serious complications. Visual result, binocular function, and patient satisfaction were generally very good.

Anterior Chamber