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Biomedical subjects

J L Pincock

Publications and source records attributed to J L Pincock.

5 recordsLinked to original sources

Auricular cartilage grafting after discectomy of the temporomandibular joint.

A consensus does not exist regarding an optimal reconstructive strategy following discectomy of the temporomandibular joint. This study presents retrospective documentation of the treatment outcome experienced with the use of autologous auricular cartilage grafting after discectomy in 26 joints. At an average follow-up slightly in excess of 2 years, this procedure appears to have approximately 85% effectiveness in producing significant relief of pain and increasing mandibular range of motion.

Adult↗

Reconstruction of cranial defects with porous hydroxylapatite blocks.

Repair of cranial defects for brain protection and aesthetics is currently a surgical problem for which there is no completely satisfactory solution. Material used for repair of cranial defects should ideally be incorporated by the body and provided a blood supply. No substance to date, including autologous bone, consistently achieves this. Hydroxylapatite is a polycrystalline, nonresorptive, biocompatible ceramic that allows osseous tissue ingrowth and ultimate transformation into vascularized bone. The authors have used granular hydroxylapatite successfully for reconstructing calvarial defects, but have experienced problems with migration of granules, prolonged mobility, and, in one patient, resorption of an underlying supporting bone graft. The use of hydroxylapatite in block form precludes most of these problems. Porous block or strips are easily contoured and can be fixed at the margin of the calvarial defect, providing immediate stability. Ingrowth of osteoblastic and fibrous tissue provides added strength and stability. This paper describes our experience with porous hydroxylapatite blocks for reconstructive cranioplasty.

Durapatite↗

Evaluation of a subcutaneously implanted hydroxylapatite-avitene mixture in rabbits.

Avitene, a microfibrillar collagen hemostatic agent was mixed with hydroxylapatite and implanted subcutaneously along the inferior border of the mandible in ten rabbits. This mixture clearly enhanced surgical manipulation of the implants. Radiographic and histologic examination of the implant sites at one, three, and six months showed an acceptable host response with no apparent alteration of the favorable characteristics of hydroxylapatite implants.

Animals↗