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Biomedical subjects

J L Sibala

Publications and source records attributed to J L Sibala.

12 recordsLinked to original sources
PubMed1981

Computed tomographic mammography. Diagnosis of mammographically and clinically occult carcinoma of the breast.

If breast cancer can be detected early, while it is still localized and before it can be palpated, the prognosis for cure is excellent. Heretofore, conventional mammography has been the only means available to detect cancer at such an early stage. Two cases of minimal breast carcinoma measuring less than 5 mm in diameter have been detected and correctly diagnosed using computed tomographic mammography (CT/M). Both cases occurred in fatty breasts and were clinically and mammographically occult. These cases demonstrate the value of CT/M in the diagnosis of minimal breast carcinoma that would have been missed otherwise.

Adult↗
PubMed1980

Computed tomography in detection and diagnosis of breast cancer.

From October 1, 1976 through July 31, 1979, at the University of Kansas Medical Center, CT/M examinations were performed on 1625 patients. Seventy-eight cancers were histologically diagnosed. A CT/M study using our contrast medium enhancement technique yields both static anatomical changes and dynamic measurements of abnormal iodide concentrations in the breast cancers. This unique ability of CT/M provides many advantages as compared with conventional mammography in the diagnosis of breast cancer. The detection rate in 78 cancers by CT/M was 94% and 77% for the mammography. The CT/M appears to be specially superior to the mammography for detecting cancers in dense, premenopausal dysplastic breasts. The CT/M can detect totally unsuspected very small breast cancers that were unable to be identified by conventional mammography or physical examinations. The CT/M scan also seems to be a better test for recognizing precancerous high risk lesions. CT/M evaluation affords definitive diagnostic help in instances where the mammographic and/or physical examinations are inconclusive. Although CT/M will not replace conventional mammography in routine breast examinations, it overcomes the limitation of mammography.

Breast↗
PubMed1978

Preoperative diagnosis of potentially precancerous breast lesions by computed tomography breast scanner: preliminary study.

Eighteen cases of severe atypical epithelial hyperplasia of the breast were detected preoperatively by computed tomography breast scanner (CT/M) with contrast enhancement. The CT number before enhancement ranged from -17 to +31 and increased to 26 to 42 after enhancement (5.2-8.4% increase in attentuation). These data suggest that CT/M can differentiate these potentially precancerous lesions from benign fibrocystic disease.

Adult↗
PubMed1978

Computed tomographic evaluation of the breast.

Experience with a dedicated breast CT scanner (General Electric CT/M) using a contrast medium enhancement technique indicates that CT is superior to mammography, thermography, or physical examination for diagnosing both benign and malignant mammary disease especially in dense, thick, or fibrocystic breasts. CT is capable of diagnosing totally unsuspected early miniature carcinomas. It can identify and differentiate potential precancerous lesions from benign fibrocystic disease, and is the diagnostic tool of choice for evaluating and following severe fibrocystic disease. CT evaluation also affords definitive diagnostic help in instances where the mammographic, thermographic, and/or physical examinations are inconclusive. It can influence immediate surgical intervention or mitigate against an unnecessary biopsy. The study not only demonstrates morphologic changes in the breast but also accurately depicts an altered iodine pool in mammary tissues.

Adult↗
PubMed1977

Computed tomography of the breast. A preliminary report.

Initial studies indicate that computed tomography can detect both benign and malignant breast disease in both fatty and dense, thick breasts. CT may also be capable of diagnosing early cancer or a precancerous lesion in women with dysplastic breasts or patients who have had radiation therapy or surgery, whereas some of these lesions cannot be diagnosed by mammography because the breast is too dense.

Breast Diseases↗
PubMed1977

A new low dose mammography technique.

Reduction of radiation dosage to patients undergoing mammography is very important, especially when large-scale screening projects for early detection of breast carcinoma are considered. A new low dose mammographic technique employing Kodak XG film and Industrex F2 intensifying screen in a vacuum package has been evaluated in 533 patients. This Kodak system was found to provide excellent diagnostic quality image, and to be an acceptable technique for mammography.

Breast Neoplasms↗
PubMed1976

Film mammography: new low radiation technology.

A new mammographic technique with Kodak MIN-R film and a Kodak MIN-R screen in a vacuum package has been evaluated in 607 cases. Direct mammographic comparison is made with the Du Pont Lo-dose system in the first 101 patients. The system provides excellent diagnostic quality images with at least a two-fold reduction in patient exposure compared to other current mammographic techniques.

Female↗