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Biomedical subjects

J L Skolnick

Publications and source records attributed to J L Skolnick.

8 recordsLinked to original sources

Blood pressure changes in patients with chronic obstructive pulmonary disease and hypertension completing phase II pulmonary rehabilitation.

A retrospective study was conducted evaluating the resting blood pressure (BP) of 160 patients at the onset and upon successful completion of a Phase II pulmonary rehabilitation program. Patients with chronic obstructive pulmonary disease (COPD) exercise at submaximal loads. Patients with both hypertension and COPD would remain hypertensive after a course of pulmonary rehabilitation. The two-tailed t-test was utilized to compare BP at the onset to BP at the completion of the program. No significant differences were found in the following groups: (1) Start and end SBP or DBP of all patients; (2) Start and end SBP or DBP of the 40 (25%) hypertensive patients (HTN-Pts); (3) Start and end SBP or DBP of the 6 (4%) HTN-Pts on antihypertensive (anti-HTN) medications; (4) Start and end SBP or DBP of the 34 (21%) HTN-Pts off anti-HTN medications. This study supports the hypothesis that HTN-Pts with COPD participating in a Phase II pulmonary rehab program remain hypertensive. Hypertension in this population should be treated medically.

Antihypertensive Agents

Blastomycosis: a reminder of Kentucky's other fungus.

Although not as common as Histoplasmosis, the disease caused by Blastomyces dermatitidis is also endemic in the Commonwealth of Kentucky. Greater clinical awareness of this systemic mycosis and the newer effective forms of treatment may lessen the significant morbidity and mortality of this potentially serious infection. To illustrate the varied manifestations of this illness, we contrast the presentation of an urban female with blastomycosis and atypical chest radiographic changes to the more classic features of blastomycosis described in the literature.

Adult

Hyperbaric oxygen treatment for carbon monoxide poisoning: observations based on 8 years experience.

Patients may develop significant carbon monoxide intoxication under a variety of circumstances. We propose that the frequency of symptoms, the patient's presentation, and ultimately the outcome are significantly related to the type of exposure. This association may help the practicing physician maintain the proper index of suspicion for recognizing carbon monoxide poisoning and providing the proper treatment for severe cases.

Adolescent

Young's syndrome: an often unrecognized correctable cause of obstructive azoospermia.

Young's syndrome consists of azoospermia owing to bilateral epididymal obstruction in patients with chronic sinus and pulmonary infections. Azoospermia may be corrected by vasoepididymostomy in these patients but postoperative fertility rates are yet to be determined. Because the infertility of Young's syndrome potentially is remediable with vasoepididymostomy and because the syndrome is observed commonly by surgeons outside of this country, we report 2 cases to illustrate what may be a frequently unrecognized and potentially correctable cause of azoospermia.

Adult

Rifampin, oral contraceptives, and pregnancy.

Rifampin is a drug used in the treatment of tuberculosis. In the literature, there are reports of seven patients who became pregnant while taking a combination of rifampin and oral contraceptives. We report an eighth case involving a woman who became pregnant twice on this drug combination.

Adult

Tussive syncope.

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Adolescent