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Biomedical subjects

J L Solka

Publications and source records attributed to J L Solka.

2 recordsLinked to original sources

A method for detecting microcalcifications in digital mammograms.

Microcalcification clusters are often an important indicator for the detection of malignancy in mammograms. In many cases, microcalcifications are the only indication of a malignancy. However, the detection of microcalcifications can be a difficult process. They are small and can be embedded in dense tissue. This paper presents a method for automatically detecting microcalcifications. We utilize a high-boost filter to suppress background clutter enabling segmentation even in very dense breast tissue. We then use a threshholding and region growing technique to extract candidate microcalcifications. Likely microcalcifications are then identified by a linear classifier. We apply this method to images selected from the LLNL/UCSF Digital Mammogram Library, and produce a receiver operating characteristic (ROC) curves to detail the trade-off between probability of detection and false alarms. Finally, we exam the ability to properly select a threshold to achieve a desired probability of detection based upon a training set. This is a US government work. There are no restrictions on its use.

Breast Neoplasms↗

The application of fractal analysis to mammographic tissue classification.

As a first step in determining the efficacy of using computers to assist in diagnosis of medical images, an investigation has been conducted which utilizes the patterns, or textures, in the images. To be of value, any computer scheme must be able to recognize and differentiate the various patterns. An obvious example of this in mammography is the recognition of tumorous tissue and non-malignant abnormal tissue from normal parenchymal tissue. We have developed a pattern recognition technique which uses features derived from the fractal nature of the image. Further, we are able to develop mathematical models which can be used to differentiate and classify the many tissue types. Based on a limited number of cases of digitized mammograms, our computer algorithms have been able to distinguish tumorous from healthy tissue and to distinguish among various parenchymal tissue patterns. These preliminary results indicate that discrimination based on the fractal nature of images may well represent a viable approach to utilizing computers to assist in diagnosis.

Breast Neoplasms↗