PubMed HealthSearch

Biomedical subjects

J L Steven

Publications and source records attributed to J L Steven.

11 recordsLinked to original sources

The EMI scanner.

Explore the source record for details and available documents.

Brain Diseases

Intracranial pressure during ventriculography using meglumine iothalamate.

A small increase in ventricular fluid pressure (1.3 +/- 0.3 mm Hg) occurs on isovolumetic addition of meglumine iothalamate to the lateral ventricle. A marked increase (46.3 +/- 3.2 mm Hg: P less than 0.001) in pressure occurs on passage of the contrast medium into the posterior part of the third ventricle; the aqueduct and the fourth ventricle. Theoretical mechanisms are discussed.

Aged

Computerized tomography in the diagnosis of cerebral atrophy.

Computerized tomograms were studied of 67 adults whose lumbar pneumoencephalograms were normal or showed ventricular dilatation with or without widening of the sulci. The maximum ventricular area, measured from 80 x 80 matrix printouts, correlates well with measures of ventricular size on the pneumoencephalogram. An area of 10 cm2 is suggested as the upper limit of normal. The correlation between measures of sulcal width on computerized tomography and pneumoencephalography is less precise, but normal sulci and gross degrees of cortical atrophy can be identified.

Adolescent

Computed tomography in the diagnosis of colloid cyst.

The diagnosis of colloid cyst of the third ventricle is notoriously difficult and contributes significantly to the high mortality. Three cases are presented in which computed tomography has contributed to the diagnosis by showing (1) the dilatation of the lateral ventricles without dilatation of the midline ventricular system, and (2) the lesion as an area of increased density within the third ventricle. Computed tomography may reduce the overall mortality in this condition by reducing the number of patients who succumb undiagnosed during an acute phase of raised intracranial pressure.

Adult

Effect of intracranial pressure of meglumine iothalamate ventriculography.

Intraventricular pressure was studied in 12 patients undergoing ventriculography with a water soluble positive contrast medium. Isovolumetric instillation of meglumine iothalamate into the lateral ventricles and the anterior part of the third ventricle caused only a small increase in ventricular fluid pressure (1.3 +/- 0.3 mmHg), but the pressure increased markedly (46.3 +/- 3.7 mmHg; P less than 0.001) when the contrast medium entered the posterior end of the third ventricle, aqueduct of Sylvius,, and fourth ventricle. This sharp increase in intracranial pressure could not be attributed solely to the postural changes or to alterations in arterial blood pressure. Possible mechanisms are discussed.

Adolescent