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Biomedical subjects

J L Tucker

Publications and source records attributed to J L Tucker.

10 recordsLinked to original sources
PubMed2001

Palladium and Raney nickel catalyzed methanolic cleavage of stable borane-amine complexes.

[figure: see text] Palladium and Raney nickel were found to catalyze the methanolysis of borane-amine adducts. Hence, strongly complexed amines can now be liberated by simple treatment with Pd/C or Raney Ni in methanol. The method is applicable to primary, secondary, tertiary, and aromatic amines, and the mildness of the reaction conditions allows preservation of otherwise labile functional groups.

Journal Article↗
PubMed2001

Patients' knowledge of health plan coverage and satisfaction with care.

OBJECTIVE: To test the hypothesis that patients' satisfaction with their healthcare is related to their knowledge of their managed care plan. STUDY DESIGN: A written survey was sent to beneficiaries of the military health system. PATIENTS AND METHODS: Respondents were active or retired military personnel and their nonmilitary, immediate family members enrolled in either TRICARE Prime, a voluntary, gatekeeper-based managed care program (enrollees), or other military managed care programs (nonenrollees). Responses to 5 questions that measured patients' understanding of their program served as independent variables; satisfaction with care was the dependent variable. Responses were stratified according to whether care was received in a military or a civilian healthcare organization. Analysis of variance (ANOVA) and regression analysis were used to determine the association between the variables. RESULTS: Enrollees differed from nonenrollees in certain sociodemographic characteristics, with nonenrollees being older (eta 2 = 0.035; P < .01), closer to retirement (eta 2 = 0.051; P < .01), and tending to receive healthcare in military healthcare organizations (HCO) (eta 2 = 0.009; P < .01). After controlling for sociodemographic characteristics, patients' understanding of their coverage served as a poor predictor (military HCO [R2 = 0.003; P < .01]; civilian HCO [R2 = 0.025; P < .01]) of satisfaction with their care. CONCLUSIONS: Patients' understanding of their coverage appears to be a statistically significant, but rather small, contributor to satisfaction with their care. The study suggests that health plan understanding is a poor predictor of patient satisfaction.

Adolescent↗
PubMed2000

The theory and methodology of provider profiling.

Physician profiling is the comparison of physician practice patterns to determine the existence and effects of significant differences in outcomes. To optimize care quality, these comparisons can be used to influence provider behavior through awareness when outcomes are poor or do not warrant provider expenditures. To maximize the value of such a technique, the underlying bases for comparison and the uses of derived data must be understood. Several factors must be considered or controlled for when determining comparable providers. Additionally, the worth or significance of findings must also be understood. This paper seeks to provide information in these two areas for the benefit of those responsible for managing care at all levels.

Benchmarking↗
PubMed2000

The influence of patient sociodemographic characteristics on patient satisfaction.

The patient satisfaction responses of active duty Army patients in military facilities were analyzed to determine (1) if patients differ along sociodemographic characteristics, (2) the predictors of satisfaction, and (3) the sociodemographic characteristics that moderate patients' satisfaction. Regression results suggest that access, communication, outcomes, and quality predict 42% of the variation in patients' satisfaction scores. Additionally, an analysis of variance suggests that patient satisfaction evaluations are significantly different along sociodemographic characteristics excepting marital status and duty location. Finally, patients' sociodemographic characteristics, with the exceptions of gender and marital status, moderate patients' satisfaction. These findings suggest that patients' satisfaction differs significantly along age, rank, gender, education, race, health status, and utilization individually, but this difference predicts only 5% of patients' satisfaction ratings. This study provides areas of consideration for improving active Army patients' satisfaction in military facilities and suggests theoretically and empirically supported ways to prioritize scarce resources and optimize efforts when faced with constraints.

Adult↗
PubMed1998

The predictors of quality care.

Patients' perceptions of quality are important to the performance ratings, financial viability, and operational options afforded to purchasers of health care. Through TRICARE, the Department of Defense provides care for the more than 1.5 million active duty service members charged with the defense of the nation. As patients, these service members are typically incapable of assessing the technical quality of the care they receive. This study examines the attributes of health care delivery that define military patients' perceptions of quality and discusses the implications of these assessments.

Adolescent↗
PubMed1998

The importance of caring as a determinant of patient satisfaction among active duty beneficiaries.

The satisfaction scores of active duty Department of Defense beneficiaries with the medical care they receive in military facilities are compared to test the hypothesis that caring is a primary determinant of patient evaluations. Patient satisfaction scores and sociodemographic and social psychological correlates of patient satisfaction were regressed to illuminate the attributes patients use to judge their health care experiences. Results show that very specific interpersonal aspects, such as reassurance, support, and interest in outcomes of the care experience, are important to patients.

Adult↗
PubMed1991

A deconvolution technique for improved estimation of rapid changes in ion concentration recorded with ion-selective microelectrodes.

In biological preparations, measurements of rapid, stimulus-evoked changes in ion concentration by ion-selective microelectrodes can be distorted by the limited bandwidth of these sensors. Techniques were developed to reconstruct the actual change in ion concentration using deconvolution of the electrode's output signal and the electrode's transfer function. In the vertebrate retina, a knowledge of the actual time course of a light-evoked increase in extracellular K+ concentration was used to provide a rigorous test of a hypothesis regarding the electrical origin of a clinically important component of the electroretinogram.

Animals↗
PubMed1990

Lovastatin decreases coenzyme Q levels in rats.

Lovastatin is used for the treatment of hypercholesterolemia. It functions by inhibiting the enzyme, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34), that is required for the conversion of 3-hydroxy-3-methylglutaryl-coenzyme A to mevalonic acid. Since biosynthesis of both cholesterol and coenzyme Q (CoQ) requires mevalonic acid as a precursor, it was considered that lovastatin therapy would also result in a lowering of cellular CoQ levels. This study was conducted to determine whether lovastatin treatment does decrease CoQ levels and whether such decreases can be prevented by CoQ supplementation. Forty-five adult male Holtzman rats were randomly assigned to one of three treatment groups. Controls were fed ground laboratory rat chow ad libitum. The other two groups were fed ground laboratory rat chow containing 400 mg of lovastatin per kg of diet ad libitum. One of the lovastatin-fed groups received CoQ10 (15 mg per kg of body weight) daily via stomach intubation. After 4 weeks, samples of heart, liver, and blood were analyzed for CoQ concentrations. Results indicated that CoQ concentrations in all tissues analyzed were decreased in lovastatin-treated rats. Lovastatin-treated animals that were supplemented with CoQ10 had blood, heart, and liver CoQ10 concentrations that approximated or exceeded those of control animals. It is concluded that lovastatin does indeed lower tissue concentrations of CoQ and that a return to normal can be achieved by supplementation with CoQ.

Animals↗
PubMed1983

Hospice care: perspectives on a Blue Cross Plan's community pilot program.

A community approach to the provision of hospice care utilizing existing community institutions in the metropolitan Washington, DC, area was started as a pilot project among three entities: the Washington Home, a licensed, skilled nursing facility, which served as the hospice inpatient unit; Georgetown University Hospital and its home care program, which were to serve as the sole referral sources; and Group Hospitalization, Inc., the local Blue Cross Plan. Insufficient referrals resulted in expansion of referral sources to include other hospice home care providers and acute care hospitals in the general community. As other community hospices developed, the Blue Cross Plan expanded the pilot program and fostered the communitywide coordination of hospice services.

Blue Cross Blue Shield Insurance Plans↗