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Biomedical subjects

J Léb

Publications and source records attributed to J Léb.

At least 19 recordsLinked to original sources
PubMed1981

Follow-up examination of patients with undescended testicles.

A detailed follow-up examination was performed in 20 patients who had been operated upon 10 to 20 years ago because of uni- or bilateral cryptorchidism. The youngest patient was 18 years old at the time of the follow-up. The following values were analysed: primary and secondary sexual characteristics, the possible sexual disturbances, penile volume and the diameter of the testes, the serum testosterone, HCG, FSH, and LH level, sperm and immune peroxidase examination, and histologic study of both testes. The absence of sexual disturbances and the normal primary and secondary sexual characteristics were explained by the results of hormonal assays and these also showed that in adults there is no possibility to improve fertility by hormones. Early operation at 2 years of age at the latest is the only possibility to prevent in- or subfertility. The intervention prevents secondary damage to the retained and to the contralateral testicle. Immune peroxidase tests pointed to the possibility of therapy by immunosuppressive drugs.

Adolescent↗
PubMed1976

Mesenteric vascular occlusion in infants and children: report of two cases and review of the literature.

Mesenteric vascular occlusion is a rare disease in the paediatric age group. The pertaining literature is reviewed and two cases are reported. In the first one the vascular obstruction developed after a Wilms tumour on the right side had been removed. Following bowel resection and end-to-end anastomosis the patient died of uraemia. Post mortem examination revealed a diffuse membranous glomerulonephritis and pseudoxanthomatosis in the remaining left kidney, the function of which had probably been affected by the shock associated with mesenteric thrombosis. In the second case a mixed mesenteric vascular occlusion was found without any previous disease; after ileal resection and ileo-coecal anastomosis the baby made a smooth recovery.

Child, Preschool↗
PubMed1975

Electrostimulation of the neuropathic bladder.

Intravesical electrostimulation offers promise in management of neurogenic bladder in children with myelocele. In the past 2 yr, we carried out about 500 treatments in 25 children aged 2 wk to 13 yr. After repeated stimulation, the starting intravesical pressure increases considerably in all cases; however, this was not always accompanied by clinical improvement. Our early results are encouraging, especially after repeated 10-day courses of electrostimulation; bladder contractions increase slowly and micturition begins to appear. Seventeen of 25 patients showed significant improvement, in two patients no improvement was observed. The remaining six have not been treated long enough to evaluate.

Adolescent↗