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J LANDON

Publications and source records attributed to J LANDON.

At least 19 recordsLinked to original sources

HERPES-LIKE VIRUS ISOLATED FROM NEONATAL AND FETAL DOGS.

A herpes-like virus has been isolated from fetal and neonatal dogs that died with an acute hemorrhagic disease. The virus differs from the other herpes-like viruses in its immunologic and growth characteristics. It is capable of passing the placental barrier and of causing disease and death of some of the fetuses, but in other apparently healthy animals the virus may remain latent, becoming activated under certain conditions.

Animals↗

Blood pyruvate concentration measured by a specific method in control subjects.

A specific method of estimating pyruvate, depending upon the oxidation of reduced nicotinamide-adenine dinucleotide in the presence of lactic dehydrogenase, has been modified to improve its accuracy. The precision of the modification, measured by duplicate analysis, was represented by a standard deviation of 0.03 mg./100 ml. The mean recovery of added pyruvate was 99%. The mean blood pyruvate concentration in 30 fasted subjects, who had no illness known to affect pyruvate metabolism, was 0.44 mg./100 ml. (S.D. 0.05). Blood pyruvate levels were measured at 30-minute intervals for two hours after oral or intravenous administration of glucose. The highest levels obtained in each case were about 0.4 mg./100 ml. higher than the initial level, and were found 60 to 90 minutes after oral administration and 30 to 60 minutes after intravenous administration.

Fasting↗