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Biomedical subjects

J LIEBERMAN

Publications and source records attributed to J LIEBERMAN.

At least 19 recordsLinked to original sources
PubMed1963

CURRENT APPRAISAL OF THROMBOLYTIC THERAPY. A CRITICAL REVIEW.

Thrombolytic therapy holds great promise for becoming an important therapeutic adjunct in the treatment of acute vascular occlusions, but such therapy has not reached the stage for general clinical use. The optimum method of administering thrombolytic agents has not yet been determined, and the processes that bring about lysis of clots are incompletely understood. Current theories in this field are reviewed and the suggested modes of therapy and potential complications are discussed.

Anticoagulants↗
PubMed1961

The fibrinolytic enzyme defect of hyaline membrane disease.

An investigation of the pulmonary fibrinolytic enzyme system in 31 infants who died with hyaline membrane formation was reviewed. There was complete lack of plasminogen activator activity in the lungs of 84 per cent of these infants. This phenomenon was shown to result from an abnormal inhibitor. A comparable inhibitor was found in normal placental tissue, and it is postulated that this inhibitor is released into the circulating blood as the result of placental infarction. Fibrin, a basic component of the hyaline membrane, is probably precipitated from a physiological capillary transudate associated with the formation of amniotic fluid by the lungs. The presence of an inhibitor of fibrinolysis would then result in the accumulation of intrapulmonary fibrin and the formation of hyaline membranes.

Amniotic Fluid↗