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Biomedical subjects

J Lachowicz

Publications and source records attributed to J Lachowicz.

6 recordsLinked to original sources

[Large-intestinal nematoda in bison].

In the Białowieza Forest the parasitological autopsy of large intestine of 6 bisons was made at the beginning of winter of 1987-1988, and 9 dissections were made in the latter part of both seasons. Four species of nematodes were found to occur together: Chabertia ovina, Oesophagostomum radiatum, Oe. venulosum and Trichocephalus ovis. At the end of wintering in bisons the invasion of Ch. ovina appeared in high percent of animals, but the intensity of it was low. However, the extensity and intensity of invasion of three remaining species of nematodes distinctly arose. In comparison with bisons in closed reserves, free living bisons assimilated Oe. venulosum and Ch. ovina. It is likely that the winter quarters are the source of invasion. It can be explained by the permanent accumulation of feaces with invasive forms of nematodes, and by feeding bisons on the great amount of hay, in which the invasive forms of nematodes may also occur.

Animals

[Harboring of helminth parasites by the European bison (Bison bonasus L.) and deer (Cervidae) in the Białowieza forest].

Parasitological autopsy of 31 european bison , 9 red-deer and 3 roe-deer was made in Białowieza Forest in the period 1983-1988. Together 20 species of nematodes were found, from them as much as 18 in bison , 6 in red-deer and 8 in roe-deer . The highest intensity and 100% of extensity was shown by nematodes from subfamily Ostertagiinae. Four species of this subfamily (O. leptospicularis, O. kolchida, S. boehmi i S. mathevossiani) have been permanently adapted by bison from cervids, however two species of nematodes typical for bison and cattle (O. ostertagii and O. lyrata) have not been adopted by deer . Besides, bison adopted from deer the following species of nematodes: T. capricola, C. pectinata, N. roscidus, N. europaeus and from moose N. alcidis. Bison gave to red-deer only C. bilobata, and roe-deer have not adopted any nematodes from bison . B. trigonocephalum and S. dagestanica found in roe-deer are in Poland typical parasites of moose .

Adaptation, Biological

Effects of prenatal dexamethasone on development of ornithine decarboxylase activity in brain and peripheral tissues of rats.

The use of glucocorticoids in the management of neonatal respiratory distress syndrome may be associated with abnormalities of growth and neurologic development. In our study, pregnant rats received either 2 or 0.2 mg/kg of dexamethasone on gestational days 17, 18, and 19 and tissues of the offspring were examined for ornithine decarboxylase activity, a marker enzyme for perturbations of cellular maturation. Acutely, the higher dose of dexamethasone suppressed ornithine decarboxylase activity in all tissues except lung, where a short-term stimulation was obtained. Repeated administration of 2 mg/kg resulted in an ornithine decarboxylase pattern consistent with delayed cellular development in all tissues (suppressed activity followed by prolonged postnatal elevations), accompanied by impaired viability and general growth. Lowering the dose of dexamethasone to 0.2 mg/kg eliminated all the adverse effects on viability but still produced perturbations of tissue ornithine decarboxylase, most notably a prolonged suppression of activity across all brain regions. These data suggest that administration of glucocorticoids even at the threshold for effects on respiratory function, may compromise neural development.

Animals

The rate of absorption of synthetic lysine and dietary protein in the upper half of the small intestine of pigs.

The aim of the present work was to estimate the rate of lysine absorption in the upper part of the small intestine as related to the absorption of total nitrogen and other amino acids in pigs given feed (barley + sesame meal) supplemented with lysine and fed once or 4 times daily. The experiments were carried out on 6 pigs fitted with reentrant cannulas sited in 3 of them about 4 m and in an other 3 about 9 m distal to the pylorus (mean intestine length was about 18 m). The frequency of feeding influenced the rate of flow of total nitrogen and lysine through the intestine. The content of lysine in the digesta (g/16 g N) during the first 5 hours after morning feeding, and particularly between 8.00-10.00 h, was much higher with once daily than with four times daily feeding while during the subsequent 15 hours the reverse was true. The absorption of lysine occurred at a faster rate than that of the other amino acids and was closest to that of arginine and methionine. On the whole, the net absorption rate of essential amino acids in the upper part of the intestine of pigs was as follows: Lys, Met greater than His, Phe, Leu greater than Trp, Ile, Val greater than Thr (Cys). It seems that the more uniform passage through and absorption from the alimentary tract of synethetic lysine and dietary protein, observed at frequent feeding could contribute to their better utilization for protein synthesis in the organism.

Animals