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J Lamprecht

Publications and source records attributed to J Lamprecht.

At least 55 records · Page 3Linked to original sources
PubMed1988

[Sinusitis and other typical ENT diseases within the scope of acquired immunologic deficiency syndrome (AIDS)].

We report our experience with 209 HIV-positive patients in different stages. A retrospective study (n = 181) showed the high frequency of lymphadenopathy, inflammatory diseases of mouth, pharynx, and esophagus (especially candidiasis) as well as other diseases such as sinusitis. A retrospective study by radiology (n = 28) showed inflammatory changes in the paranasal sinuses in patients with LAS, ARC, and AIDS.

AIDS-Related Complex↗
PubMed1987

Mitosis in the corneal epithelium. A preliminary communication on the coexistence of differential and equivalent cell divisions.

The morphology and orientation of cytokinetic figures were studied in the rat corneal epithelium by light microscopy using serial semi-thick plastic sections. It has been found that the mitotising cell of the basal epithelial layer produces either a pair of morphologically similar daughter cells--equivalent or symmetrical division or a pair of morphologically dissimilar cells--differential or asymmetrical division. The equivalent divisions are horizontally orientated, whereas the differential divisions are oblique or vertical in relation to the basement membrane.

Animals↗
PubMed1987

[Mediastinal involvement in cancers of the subglottis, hypopharynx and cervical esophagus].

In carcinoma of subglottis, hypopharynx, and cervical oesophagus there is a high risk of mediastinal involvement by continuous infiltration of lymphogeneous metastatic spread because of tight neighbourhood. In progress of the disease we saw mediastinal involvement in 46.2% of subglottic carcinoma (n = 26), and in 44.1% of hypopharyngeal carcinoma (n = 79). Stomal recurrence after laryngectomy or tumour invasion of the oesophagus appeared to signify regularly mediastinal involvement. We recommend high attentiveness to the caudal borderline resection, to aspire complete oesophagectomy in cases of oesophageal cancer, and to include mediastinum into postoperative radiation area.

Esophageal Neoplasms↗
PubMed1987

Frequency of occurrence and distribution of the intra-epithelial lymphoid cells in the follicle-associated epithelium in phenotypically normal and athymic nude mice.

We have determined the number and pattern of spatial distribution of intraepithelial lymphoid cells in the follicle-associated epithelium of Peyer's patches and in the villus epithelium in the small intestine of athymic nu/nu mice and of the phenotypically normal mice kept in specified pathogen-free conditions. The results were obtained by histometric analysis of semithin histological sections. It has been found that the lymphoid cells were scattered randomly in the villus epithelium, while those in the follicle-associated epithelium were non-randomly distributed, occurring often in groups of several cells both for athymic nu/nu and phenotypically normal mice. The numbers of lymphoid cells in the follicle-associated and in the villus epithelium were found to be significantly lower in athymic nu/nu mice than in phenotypically normal mice kept in similar conditions. On the basis of the above results the proportions of thymus-dependent and thymus-independent lymphoid cells in the intestinal epithelium were deduced.

Animals↗
PubMed1986

Spatial orientation of the mitotic apparatus and its stability in a polarized epithelial cell. A computer-assisted morphometric analysis.

The spatial and temporal orientation of the mitotic apparatus in reference to the polarized structure of an epithelial cell, as well as the relationship between mitotic spindle positioning and the direction of epithelial cell migration, was investigated. As an experimental model the epithelium of the mouse small intestine was chosen. Computer-assisted morphometric analysis applied in this study disclosed that the position of the mitotic spindle axis is restricted to a plane which is perpendicular to the axis of cell polarity. On this plane the spindle axis may occupy a random position. The latter finding indicates that there exists no correlation between the orientation of the mitotic spindle and the direction of epithelial cell migration. The plane of the spindle axis is established at metaphase, and no repositioning at further stages of mitosis has been observed. It is suggested that cell polarity plays a role in determination and stabilization of the mitotic spindle orientation in epithelial cells.

Animals↗
PubMed1986

Positioning and stability of mitotic spindle orientation in the neuroepithelial cell.

To verify non-random positioning and to define the stability of the mitotic spindle orientation in neuroepithelial cells of mouse foetuses, computer - assisted morphometric analysis at the light microscopy level was performed. It was confirmed that the mitotic spindle axis is positioned non-randomly in relation to the cell polarity axis and could be displaced only within a narrow range. This orientation was found to be attained at metaphase and it does not change until telophase is completed. However, in relation to the long axis of the neural tube the mitotic spindle axis was found to be positioned randomly. In the light of these findings centrosome movement and positioning are discussed.

Animals↗
PubMed1986

[AIDS in ENT practice--case report and review].

We present a case of AIDS with Kaposisarcoma in the oropharynx. In this case chemotherapy and radiotherapy were used with good response. Because of the clinical features of the disease otolaryngologists will be involved more and more in the management of AIDS disease. The diagnosis, therapy, and prognosis of the following three stages are described: serological identification of antibodies against HTLV-III without clinical symptoms, AIDS-related complex, full-blown-AIDS. There is no inevitable transition between these stages. The mode of infection is similar to serum-hepatitis.

Acquired Immunodeficiency Syndrome↗
PubMed1985

[Perilymph fistulas--symptoms and indications for tympanoscopy].

In the last two years thirteen cases of perilymph fistula were treated by tympanoscopy and covering with connective tissue. Recovery of hearing was not observed in 4 totally deaf ears, but improvement was recorded in each of 9 cases with impaired hearing. Vertigo disappeared in 10 of 11 cases without any correlation with the degree of hearing loss. We perform tympanoscopy in suspected perilymph fistula, because prognosis is uncertain, spontaneous recovery with remaining defects may induce ménièriform syndrome, and pathway of infection should be closed. The diagnosis of a perilymph fistula must be solidified in cases of sudden deafness with vertigo, sudden hearing loss changing to the worse during medical treatment, sudden hearing loss without recovery during medical treatment, sudden hearing loss and subsequent onset of vertigo.

Adult↗
PubMed1985

[Bilateral caloric long-term irrigation as a method for the differentiation of tonal tinnitus].

In 307 subjects with tinnitus aurium, the parameters frequency, loudness, and masking levels did not correlate significantly with the basic diseases. As a new possibility in differentiation between tinnitus of central or peripheral origin, bilateral caloric long-term irrigation of the ear canal is presented. Using warm water leads to an increase, cold water to a decrease in the loudness of tinnitus. Such results were found in cases of Menière's disease and noise-induced hearing loss. An explanation of this phenomenon lies in the hypothesis of tinnitus genesis established by Tonndorf.

Adult↗
PubMed1985

[Significance of the glycerol test for the diagnosis of sensorineural hearing disorders].

140 patients with various forms of sensorineural hearing loss were examined via the glycerol test (Klockhoff). In 66% of the cases with Menière's disease, a typical temporary threshold shift could be seen. 17 patients with fluctuating hearing loss of unknown etiology without vestibular symptoms showed a similar effect; they were classified as belonging to the group of the cochlear type of Menière's disease. In 34% of cases with clinically assured diagnosis of Ménière's disease, glycerol did not induce improvement in hearing. Repeated glycerol tests revealed varying results; shortly after a Menière attack, the glycerol test was usually negative, whereas shortly before the next attack the glycerol test changed to positive. These data support the specificity of the glycerol test: The results depend on the presence of endolymphatic hydrops at the time of examination. Positive results of the glycerol test were also seen in the cases of reduced sensorineural hearing associated with syphilis, as well as in cases of cerebrospinal pressure changing synchronously with fluctuating hearing loss (Lindsay and Zajtschuk). In all other cases of sensorineural hearing losses, no positive effect of the glycerol test has been found.

Audiometry, Pure-Tone↗
PubMed1985

[Hearing loss in childhood combined with abnormalities].

Hearing loss was diagnosed in 923 of 1712 children attending our paedaudiology outpatient department over a period of two years. 14% of patients with hearing loss had one or more associated malformations, affecting the musculoskeletal system, the heart, the eye and central nervous system. Metabolic disorders were also found. In addition to specific otologic procedures such as surgery and hearing aids a close cooperation with several specialists, in particular human geneticists, is necessary.

Abnormalities, Multiple↗
PubMed1984

Non-random distribution of intraepithelial lymphoid cells in follicle-associated epithelium of Peyer's patches in mice.

The spatial distribution of intraepithelial lymphoid cells in follicle-associated and villus epithelium within Peyer's patches was studied quantitatively in Balb/C and CFW/L1 mice. The results were essentially the same for both strains. The distribution of the number of lymphoid cells per segmental length (equal to an average width of an epithelial cell) of dome epithelium was found to be non-random, since it deviated significantly from the theoretical Poisson distribution. Some segments of the dome epithelium, therefore, are lymphocyte-rich and some are lymphocyte-depleted, i.e. they contain either more, or less lymphoid cells than expected from the random distribution. This was in contrast to the distribution in the epithelial layer of the villi, in which the distribution of the number of lymphoid cells per segment followed the Poisson distribution. It was also demonstrated that segments rich in lymphocytes in the dome epithelium occurred in series or clusters. Lymphoid cell clustering was not observed in the villus epithelium. Possible mechanisms responsible for the non-random spatial distribution of lymphoid cells within the dome epithelium of the mouse Peyer's patches are discussed.

Animals↗
PubMed1983

[Multiple tumors in the upper aerodigestive tract--a retrospective study].

The authors observe an increasing incidence of multiple primary neoplasms in the upper aerodigestive tract. Out of 1231 patients with neoplasms, 110 (= 8.9%) developed another tumour. Following oral cavity tumours the incidence of second tumours was twice as high as in other localities. Privileged site of second tumours following cancer of the larynx is the lung, after oral cavity neoplasms the hypopharynx and larynx. The mean interval between first and secondary neoplasms was 4.4 years. In tumour follow-up therapy it is recommended to look not only for relapses and metastases but also for second tumours.

Germany, West↗
PubMed1983

[Pathogenesis and clinical aspects of Ménière disease. A study of 739 patients].

The symptomatology of Ménièr's disease is delineated by means of 739 cases observed in a period of 25 years. The dilation of the endolymphatic space accompanied by a temporary mixture of endolymph and perilymph substantiates the idea of a nosologic entity as well as the interpretation of the symptoms: vertigo, fluctuating hearing loss, tinnitus, and fullness of the ear. The medical treatment by infusions of Rheomacrodex, vasodilatory substances, antivertiginosa, and psychosedatives is unsatisfying just as surgical treatment by saccotomy, sacculotomy, labyrinthectomy, and other operations at the inner ear. Local application of gentamycin into the middle ear can produce good results; in cases of failure the neurectomy should be taken in consideration. The neurectomy eliminates vertigo, but there remains the need of central compensation and the possibility of appearance of Ménière's disease on the other ear.

Adult↗