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Biomedical subjects

J Lasek

Publications and source records attributed to J Lasek.

17 recordsLinked to original sources
PubMed2000

Modern approach to management of patients following major trauma.

Trauma remains one of the three main causes of death all over the world. In Poland severe trauma is also an important public health problem which should be fully recognised in the changing system of our health service. There is a growing understanding and interest in the integration of pre-hospital, in-hospital and rehabilitation services taking part in the management of trauma patients. The importance of emergency medicine departments has been found valuable in Western countries and should be promoted by all means in our country. Certain recommendations of treatment of patients following severe trauma have been discussed concerning anti-shock therapy, diagnostic and operative management in polytraumatized patients with major head trauma, thoracic and abdominal trauma and also operative stabilization of fractures of bones. It has been concluded that in our country, especially in bigger cities, patients following major trauma should be treated in specially designed units (centers) integrated with emergency medicine departments providing competent intensive therapy and surgical interventions of well trained trauma teams introducing optimal modern trauma algorithms.

Craniocerebral Trauma↗
PubMed1997

[Selected injury severity scales for practical use in traumatology].

Measurement of severity of injuries is by all means needed in contemporary traumatology. Objective assessment of several different injuries is helpful in different comparisons concerning different groups of trauma patients. The authors have chosen 4 number scales: Trauma Scale (TS), Abbreviated Injury Scale (AIS), Injury Severity Score (ISS) and APACHE (Acute Physiology and Chronic Health Evaluation) in order to assess their application in traumatological practice. Advantages and disadvantages of number scaling describing of severity of injuries in trauma patients have been discussed.

Humans↗
PubMed1997

[Preventable deaths after severe trauma].

A detailed analysis of 234 trauma patients who died after being admitted to the Department of Trauma Surgery in 1990-1996 has been performed in prospective studies. Among all fatalities multiple injuries have been diagnosed in 86 persons (36.7%) while single injuries have been found in 148 persons (63.3%). The mean Injury Severity Score (ISS) was 18. Consequences of severe head injuries, cardio-pulmonary complications, shock and pulmonary artery embolism have been identified as the main causes of death. All fatal cases have been reviewed by a multidisciplinary panel of physicians and judged as nonpreventable or preventable. In 28 cases errors and deficiencies leading to death have been identified and thus the overall preventable death rate (PDR) was 11.9%. PDR has been much higher among multiply injured patients than in patients with single injuries. Preventable diagnostic errors and deficiencies in management of multiply injured patients have been committed mainly in the early resuscitative phase. A decrease of PDR in fatalities treated lately in our Department has been recorded. Other aspects concerning studies on preventability in trauma patients have been discussed.

Adolescent↗
PubMed1997

[Enzymatic markers in peritoneal lavage fluid for diagnosis of blunt abdominal trauma].

Value of Diagnostic Peritoneal Lavage (DPL) in blunt abdominal trauma has been analysed in the studies. The material included 84 patients who were subjected to DPL since 1990 till 1994, and who were treated in the Department of Trauma Surgery Medical University of Gdańsk. The enzymatic examination of the lavage perfusate performed in this study revealed that the level of the activity of the aspartic transaminase and the alanine transaminase over 10 IU/L indicate hepatic injury, and the level of the alkaline phosphatase over 3 IU/L point at the injury of the large intestine, small intestine and mesentery.

Alanine Transaminase↗
PubMed1994

[A case of large bowel injury with a safety belt in a pregnant woman].

The authors present the case of a 24-year-old pregnant woman (9th week of pregnancy) who, due to a traffic accident, suffered transverse colon rupture through a sudden compression of the intestine with a "traditional" safety belt. The authors analyse the mechanism of injury, method of treatment, and on the basis of literature data discuss various body injuries developing as a result of action of safety belts.

Accidents, Traffic↗
PubMed1990

The effect of zinc oxide on Staphylococcus aureus and polymorphonuclear cells in a tissue cage model.

The effect of zinc oxide on S. aureus (209 P) was studied in steel net tissue cages implanted subcutaneously in guinea pigs and rabbits. Zinc oxide installed in the tissue cages created high, sustained concentrations of zinc in the cage fluid throughout the study. In a concentration of 22 mmol/l zinc oxide reduced viable counts in tissue cage fluid inoculated with S. aureus. No deleterious effect was observed on polymorphonuclear cell function.

Animals↗
PubMed1985

The effect of topical zinc absorption from wounds on growth and the wound healing process in zinc-deficient rats.

An experiment with local application of zinc oxide from a zinc tape to wounds was performed on 80 male Sprague-Dawley rats. Tapes with or without zinc oxide were applied on excisional wounds of both zinc-deficient and zinc-sufficient animals. The reduction in wound area was more pronounced in zinc-tape-treated animals given both a zinc-deficient and zinc-sufficient diet. The operative trauma had a negative effect on the animals' growth rate, although the state of zinc deficiency in the operated rats could be relieved by the local application of zinc. The results of the present study indicate that topically absorbed zinc from wounds promotes both the early wound healing phase and growth in both zinc-deficient and zinc-sufficient rats.

Administration, Topical↗
PubMed1976

Ultrastructure of cells of proper gastric glands and their stroma in hemorrhagic shock in the rat.

Ultrastructural changes in the cells of the proper gastric glands and their stroma are biphasic in the hemorrhagic shock. First phase: "paralysis" of the capillary vessels with an oedema of their stroma, an intracellular oedema with hydropic degeneration of the parietal cells and a degranulation of the argentaffin and argentaffin-like cells. Second phase: ischemia of the gastric mucosa with ultrastructural features of: a) the increased secretion of the parietal cells, b) the degranulation of the chief gastric cells, c) the increased secretion processes in the mucous neck cells. These findings suggest that at last 2 factors coincide in the pathogenesis of so-called stress gastric ulcerations: biphasic disturbances of blood circulation initially damage the gastric mucosa and are followed the digestive hyperactivity of the gastric juice finally resulting stress ulceration.

Animals↗